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Juvenile myelomonocytic leukemia
(Juvenile_myelomonocytic_leukemia)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
KRAS 1 -0.510 0.620 1.031 0.887
KRAS 1 -0.510 0.620 0.246 -0.346
NRAS 1 1.810 -0.720 0.246 -0.346
PTPN11 0 -0.210 -0.400 0.644 1.053 0.451
NF1 0 1.000 -0.500 0.444 -0.190

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
KRAS Ubiquitylation K128 1.528 1.433 _TVDTK(gl)QAHELAK_
KRAS Ubiquitylation K235 0.591 0.087 _TVDTK(gl)QAQDLAR_
KRAS Ubiquitylation K254 -0.450 -0.156 _SYGIPFIETSAK(gl)TR_
NF1 Ubiquitylation K471 0.218 _MAPSLTFKEK(gl)_
NF1 Phosphorylation S864 -0.458 _SNSGLATYS(ph)PPMGPVSER_
NF1 Phosphorylation T2514 0.076 _GSEGYLAATYPTVGQT(ph)SPR_
NF1 Phosphorylation S2515 0.071 0.316 _GSEGYLAATYPTVGQTS(ph)PR_
NF1 Phosphorylation S2543 0.698 0.655 _S(ph)FDHLISDTK_
NRAS Ubiquitylation K128 1.528 1.433 _TVDTK(gl)QAHELAK_
PTPN11 Ubiquitylation K124 0.562 _EAEK(gl)LLTEK_


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