Results for the Category
3'-5'-exoribonuclease activity
(GO:0000175)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| EXOSC3 | 1 | -1.840 | 3.020 | -0.152 | -0.472 | -0.227 | -0.542 | -0.121 |
| PNPT1 | 1 | -1.420 | 2.630 | 1.469 | -0.694 | 0.280 | 0.483 | |
| CNOT8 | 1 | -1.460 | 2.820 | |||||
| EXOSC7 | 0 | 0.320 | 0.360 | 0.498 | -0.198 | 0.040 | 0.896 | -0.129 |
| EXOSC5 | 0 | -1.260 | 2.170 | |||||
| EXOSC5 | 0 | -1.260 | 2.170 | 0.148 | 0.414 | |||
| DIS3 | 0 | 0.150 | -0.690 | |||||
| DIS3 | 0 | 0.150 | -0.690 | -0.335 | -0.438 | -0.111 | ||
| EXOSC9 | 0 | 0.080 | 0.519 | 0.128 | -0.495 | 0.107 | ||
| EXOSC2 | 0 | -0.410 | 0.130 | -0.167 | 0.162 | 0.416 | -0.803 | 0.148 |
| PAN2 | 0 | -0.210 | 0.670 | |||||
| CNOT7 | 0 | 0.480 | -0.730 | -0.386 | ||||
| CNOT7 | 0 | 0.480 | -0.730 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| CNOT7 | Ubiquitylation | K200 | -1.098 | -0.157 | _YLMK(gl)SCK_ |
| CNOT8 | Ubiquitylation | K200 | -1.098 | -0.157 | _YLMK(gl)SCK_ |
| CNOT8 | Ubiquitylation | K269 | -0.696 | -0.445 | _LYGLGTGVAQK(gl)QNEDVDSAQEK_ |
| DIS3 | Ubiquitylation | K337 | -0.491 | _TAVSEK(gl)MLKPTGR_ | |
| DIS3 | Ubiquitylation | K535 | -0.201 | _RGTTVYLCEK(gl)R_ | |
| EXOSC2 | Ubiquitylation | K70 | -0.209 | _LICVK(gl)ALK_ | |
| EXOSC2 | Ubiquitylation | K97 | 0.060 | _WK(gl)VETNSR_ | |
| EXOSC2 | Phosphorylation | S175 | -0.346 | -0.185 | _LGQGVLVQVS(ph)PSLVK_ |
| EXOSC2 | Ubiquitylation | K180 | -0.618 | _LGQGVLVQVSPSLVK(gl)R_ | |
| EXOSC5 | Ubiquitylation | K68 | -1.576 | _VSK(gl)EIFNK_ | |
| EXOSC5 | Ubiquitylation | K92 | -1.386 | 0.381 | _IGLPGVAEK(gl)SR_ |
| EXOSC5 | Ubiquitylation | K191 | -0.124 | _K(gl)LLMSSTK_ | |
| EXOSC9 | Ubiquitylation | K52 | 0.195 | _ISFGTDYGCCIVELGK(gl)TR_ | |
| EXOSC9 | Phosphorylation | S306 | 0.254 | 0.180 | _APIDTS(ph)DVEEK_ |
| PAN2 | Phosphorylation | S671 | 0.047 | 0.183 | _CGS(ph)ETVRAS(ph)STLLFT(ph)LS(ph)YPDGS(ph)K_ |
| PAN2 | Phosphorylation | S677 | 0.047 | 0.183 | _CGS(ph)ETVRAS(ph)STLLFT(ph)LS(ph)YPDGS(ph)K_ |
| PAN2 | Phosphorylation | T683 | 0.047 | 0.183 | _CGS(ph)ETVRAS(ph)STLLFT(ph)LS(ph)YPDGS(ph)K_ |
| PAN2 | Phosphorylation | S685 | 0.047 | 0.183 | _CGS(ph)ETVRAS(ph)STLLFT(ph)LS(ph)YPDGS(ph)K_ |
| PAN2 | Phosphorylation | S690 | 0.047 | 0.183 | _CGS(ph)ETVRAS(ph)STLLFT(ph)LS(ph)YPDGS(ph)K_ |
| PAN2 | Ubiquitylation | K706 | 0.506 | _NYDFAQVLK(gl)R_ | |
| PAN2 | Phosphorylation | S791 | 0.606 | 0.694 | _ELGS(ph)PEGVLVCPSIEELK_ |
| PAN2 | Ubiquitylation | K997 | -2.499 | _SDGTK(gl)STIKPSQMSVAR_ |
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