Results for the Category
Early-onset autosomal dominant Alzheimer disease
(Early-onset_autosomal_dominant_Alzheimer_disease)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| PSEN2 | 1 | -1.820 | 3.280 | |||||
| PSEN1 | 0 | 0.930 | -1.110 | |||||
| APP | 0 | 0.100 | -0.260 | 0.285 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| APP | Ubiquitylation | K751 | -1.778 | -1.280 | _HLSK(gl)M(ox)QQNGYENPTYK_ |
| PSEN1 | Phosphorylation | S313 | 0.844 | _VSKNS(ph)KYNAESTER_ | |
| PSEN1 | Ubiquitylation | K314 | 0.016 | 0.414 | _NSK(gl)YNAESTER_ |
| PSEN1 | Phosphorylation | S366 | -0.340 | 0.055 | _AAVQELSS(ph)SILAGEDPEER_ |
| PSEN1 | Phosphorylation | S367 | 0.005 | 0.066 | _AAVQELSSS(ph)ILAGEDPEER_ |
| PSEN2 | Phosphorylation | S58 | -0.112 | -0.130 | _TSLM(ox)SAES(ph)PTPR_ |
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