bioLOGIC Category
Results for the Category
CIN85 complex (CIN85, CRK, BCAR1, CBL, PIK3R1, GRB2, SOS1)
(2480)
| RNAi screen result
|
RNAPII IP (MG132) |
CSB IP |
CSB IP (MG132) |
Chrom. |
Chrom. (MG132) |
Ubi /Phospo |
Ubi /Phospho (MG132) |
| W |
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| Gene name |
MGoogle Score |
RNAi high |
RNAi low |
RNAPII-IP (MG132) |
CSB-IP |
CSB-IP (MG132) |
Chrom. |
Chrom. (MG132) |
|
SOS1
|
0
|
0.500
|
-0.620
|
-0.570
|
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PIK3R1
|
0
|
1.910
|
-1.220
|
|
|
|
-0.441
|
0.147
|
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SH3KBP1
|
0
|
-0.400
|
-0.020
|
-0.522
|
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CRK
|
0
|
-0.790
|
0.230
|
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GRB2
|
0
|
-0.240
|
0.300
|
|
-1.021
|
0.057
|
0.906
|
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| Gene name |
PTM type |
PTM site |
UV |
UV (MG132) |
Sequence |
|
CRK
|
Phosphorylation
|
S40
|
0.533
|
0.363
|
_DS(ph)STSPGDYVLSVSENSR_
|
|
CRK
|
Phosphorylation
|
S41
|
1.065
|
0.801
|
_DSS(ph)TSPGDYVLSVSENSR_
|
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GRB2
|
Ubiquitylation
|
K10
|
0.146
|
|
_YDFK(gl)ATADDELSFK_
|
|
GRB2
|
Ubiquitylation
|
K20
|
-0.078
|
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_ATADDELSFK(gl)R_
|
|
GRB2
|
Ubiquitylation
|
K69
|
-0.362
|
0.641
|
_AK(gl)AEEMLSK_
|
|
GRB2
|
Ubiquitylation
|
K76
|
0.754
|
|
_AEEMLSK(gl)QR_
|
|
GRB2
|
Ubiquitylation
|
K109
|
0.381
|
-0.002
|
_FGNDVQHFK(gl)VLR_
|
|
SH3KBP1
|
Phosphorylation
|
S230
|
0.300
|
0.186
|
_S(ph)IEVENDFLPVEK_
|
|
SOS1
|
Phosphorylation
|
S1082
|
0.278
|
|
_IPESETESTASAPNS(ph)PR_
|
|
SOS1
|
Phosphorylation
|
S1166
|
0.097
|
-0.094
|
_RPESAPAES(ph)SPSK_
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© Copyright Svejstrup Laboratory 2015