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Query: ZW10

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ZW10 0 1.162 -0.220 0.840 -0.532 0.113 0.496 0.629

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ZW10 Ubiquitylation K777 -0.384 _AAALAK(gl)IK_

Background Information for ZW10:


Pubmed-ZW10 »
Uniprot-ZW10 »
Biogrid-ZW10 »
ProteomicsDB-ZW10 »

Tumorportal-ZW10 »
COSMIC-ZW10 »
GenomeRNAi-ZW10 »
Genecards-ZW10


Protein-protein Interactions for ZW10
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait LDHD Cat. description Hein, Mann, Cell 2015
Category members IP bait SLC33A1 Cat. description Hein, Mann, Cell 2015
Category members IP bait XRCC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait ZW10 Cat. description Hein, Mann, Cell 2015
Category members IP bait BSG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CHRM4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FZD10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait OPRM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RINT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCFD2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SEC22B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STX18 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait USE1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VAMP4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VIPR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ZW10
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RZZ-complex_Zw10 IPR009361 0


Protein complexes (CORUM database) featuring ZW10
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 705 SNARE complex (RINT1, ZW10, p31) Database 0.05


Categories featuring ZW10
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members Pathway Pathway_321 REACTOME_MITOTIC_M_M_G1_PHASES 0 5.47
Category members Pathway Pathway_323 REACTOME_DNA_REPLICATION 0 5.24
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members GO Category GO:0015031 protein transport Database 3.48
Category members Pathway Pathway_726 REACTOME_MITOTIC_PROMETAPHASE 0 2.41
Category members GO Category GO:0000776 kinetochore Database 2.24
Category members GO Category GO:0007067 mitosis Database 2.23
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0006461 protein complex assembly Database 0.57
Category members GO Category GO:0000922 spindle pole Database 0.35
Category members GO Category GO:0000777 condensed chromosome kinetochore Database 0.32
Category members GO Category GO:0000132 establishment of mitotic spindle orientation Database 0.29
Category members GO Category GO:0000775 chromosome, centromeric region Database 0.29
Category members GO Category GO:0006888 ER to Golgi vesicle-mediated transport Database 0.28
Category members GO Category GO:0007093 mitotic cell cycle checkpoint Database 0.27
Category members GO Category GO:0019237 centromeric DNA binding Database 0.23
Category members GO Category GO:0007096 regulation of exit from mitosis Database 0.07
Category members GO Category GO:0007080 mitotic metaphase plate congression Database 0.04
Category members GO Category GO:0007126 meiosis Database 0.01
Category members GO Category GO:0000070 mitotic sister chromatid segregation Database 0
Category members GO Category GO:0005828 kinetochore microtubule Database 0
Category members GO Category GO:0034501 protein localization to kinetochore Database 0


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