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Query: ZNF483

This is a cancer-associated gene according to the Broad cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ZNF483 0 0.614

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ZNF483 Phosphorylation S14 0.007 0.607 _M(ox)TAIS(ph)PEPQTLASTEQNEVPR_

Background Information for ZNF483:


Pubmed-ZNF483 »
Uniprot-ZNF483 »
Biogrid-ZNF483 »
ProteomicsDB-ZNF483 »

Tumorportal-ZNF483 »
COSMIC-ZNF483 »
GenomeRNAi-ZNF483 »
Genecards-ZNF483


Protein-protein Interactions for ZNF483
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CCDC59 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DGCR8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MECP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VTN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR46 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF18 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF483 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ZNF483
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Krueppel-associated_box IPR001909 2.12
Category members Znf_C2H2-like IPR015880 1.29
Category members Znf_C2H2 IPR007087 0.92
Category members Tscrpt_reg_SCAN IPR003309 0.22
Category members Retrov_capsid_C IPR008916 0.13


Protein complexes (CORUM database) featuring ZNF483
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ZNF483
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members Human mutations Broad_cancer_genes Broad cancer genes (Lawrence et al., 2014) literature 1.14
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0005622 intracellular Database 0.32
Category members Pathway Pathway_822 REACTOME_GENERIC_TRANSCRIPTION_PATHWAY 0 0.09
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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