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Query: ZNF446

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ZNF446 0 -2.186 1.270 -0.700

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ZNF446 Phosphorylation S137 -0.997 -1.189 _TEEPLGS(ph)PHPSGTVESPGEGPQDTR_

Background Information for ZNF446:


Pubmed-ZNF446 »
Uniprot-ZNF446 »
Biogrid-ZNF446 »
ProteomicsDB-ZNF446 »

Tumorportal-ZNF446 »
COSMIC-ZNF446 »
GenomeRNAi-ZNF446 »
Genecards-ZNF446


Protein-protein Interactions for ZNF446
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ALDH3A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LEPRE1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PGBD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RFPL4B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RGS3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR85 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait XAGE1A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZKSCAN4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF18 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF232 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF24 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF263 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF396 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF397 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF434 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF444 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF483 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF576 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ZNF446
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Krueppel-associated_box IPR001909 2.12
Category members Znf_C2H2-like IPR015880 1.29
Category members Znf_C2H2 IPR007087 0.92
Category members Tscrpt_reg_SCAN IPR003309 0.22
Category members Retrov_capsid_C IPR008916 0.13


Protein complexes (CORUM database) featuring ZNF446
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ZNF446
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0006357 regulation of transcription from RNA polymerase II promoter Database 0.19
Category members Pathway Pathway_822 REACTOME_GENERIC_TRANSCRIPTION_PATHWAY 0 0.09
Category members GO Category GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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