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Query: YARS2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
YARS2 0 1.774 -1.060 1.490 0.747 -0.546 0.181 -0.098

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for YARS2:


Pubmed-YARS2 »
Uniprot-YARS2 »
Biogrid-YARS2 »
ProteomicsDB-YARS2 »

Tumorportal-YARS2 »
COSMIC-YARS2 »
GenomeRNAi-YARS2 »
Genecards-YARS2


Protein-protein Interactions for YARS2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MRPL50 Cat. description Hein, Mann, Cell 2015
Category members IP bait APOBEC3D Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ATP5D Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDC20 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CIRBP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DDX28 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FASTKD2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HNRNPA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HNRPDL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLHL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPL12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPL39 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPL4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NXF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBM3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBM42 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBMX Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPUSD3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM184A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRUB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UQCC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait YARS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZC3H3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF324B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in YARS2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members aa-tRNA-synth_Ic IPR002305 0.01
Category members Tyr-tRNA-ligase IPR002307 0


Protein complexes (CORUM database) featuring YARS2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring YARS2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0006412 translation Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members Pathway Pathway_202 REACTOME_TRNA_AMINOACYLATION 0 1.34
Category members GO Category GO:0006418 tRNA aminoacylation for protein translation Database 0.91
Category members Pathway Pathway_409 KEGG_AMINOACYL_TRNA_BIOSYNTHESIS 0 0.82
Category members GO Category GO:0005759 mitochondrial matrix Database 0.59
Category members GO Category GO:0004812 aminoacyl-tRNA ligase activity Database 0.41
Category members Pathway Pathway_203 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION 0 0
Category members Disease phenotype Mitochondrial_myopathy_and_sideroblastic_anemia Mitochondrial myopathy and sideroblastic anemia Database 0
Category members GO Category GO:0000049 tRNA binding Database 0
Category members GO Category GO:0004831 tyrosine-tRNA ligase activity Database 0
Category members GO Category GO:0006437 tyrosyl-tRNA aminoacylation Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0043039 tRNA aminoacylation Database 0


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