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Query: XPO5

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
XPO5 0 0.669 -0.730 0.620 -0.115 -0.423
XPO5 0 0.669 -0.730 0.620 -1.249

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
XPO5 Ubiquitylation K41 0.335 0.432 _FCEEFK(gl)EK_
XPO5 Ubiquitylation K930 0.307 _LSQK(gl)WQVINQR_
XPO5 Ubiquitylation K208 0.222 _YQQVK(gl)TDTSQESK_
XPO5 Ubiquitylation K590 0.136 _LFSSVTFETVEESK(gl)APR_
XPO5 Ubiquitylation K610 1.403 -0.701 _HACSSIIK(gl)M(ox)CR_
XPO5 Ubiquitylation K413 -0.446 -1.260 _MGFPSK(gl)TDSPSCEYSR_
XPO5 Ubiquitylation K981 0.854 _EVMDLITVCCVSKK(gl)_
XPO5 Ubiquitylation K1181 -0.022 _NLPSLFKK(gl)_

Background Information for XPO5:


Pubmed-XPO5 »
Uniprot-XPO5 »
Biogrid-XPO5 »
ProteomicsDB-XPO5 »

Tumorportal-XPO5 »
COSMIC-XPO5 »
GenomeRNAi-XPO5 »
Genecards-XPO5


Protein-protein Interactions for XPO5
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait HSPA5 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF20B Cat. description Hein, Mann, Cell 2015
Category members IP bait PCNA Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB11A Cat. description Hein, Mann, Cell 2015
Category members IP bait ZNF673 Cat. description Hein, Mann, Cell 2015
Category members IP bait CLEC12A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DKFZp686O24166 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PVR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RALB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VSIG2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in XPO5
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members Importin-beta_N IPR001494 0
Category members Exportin-1/Importin-b-like IPR013598 0


Protein complexes (CORUM database) featuring XPO5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 3080 ILF3-XPO5 complex Database 0.04


Categories featuring XPO5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005488 binding Database 9.32
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0006886 intracellular protein transport Database 2.48
Category members GO Category GO:0008565 protein transporter activity Database 0.26
Category members GO Category GO:0008536 Ran GTPase binding Database 0.21
Category members Pathway Pathway_368 REACTOME_MICRORNA_MIRNA_BIOGENESIS 0 0.18
Category members Pathway Pathway_379 REACTOME_REGULATORY_RNA_PATHWAYS 0 0.12
Category members GO Category GO:0000049 tRNA binding Database 0
Category members GO Category GO:0006611 protein export from nucleus Database 0
Category members GO Category GO:0031047 gene silencing by RNA Database 0


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