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Query: XBP1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
XBP1 0 -0.358 0.460 0.310

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
XBP1 Phosphorylation S47 -0.358 _GAS(ph)PEAASGGLPQAR_

Background Information for XBP1:


Pubmed-XBP1 »
Uniprot-XBP1 »
Biogrid-XBP1 »
ProteomicsDB-XBP1 »

Tumorportal-XBP1 »
COSMIC-XBP1 »
GenomeRNAi-XBP1 »
Genecards-XBP1


Protein-protein Interactions for XBP1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CCDC102B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CROCC Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in XBP1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members bZIP IPR004827 0
Category members TF_DNA-bd IPR008917 0


Protein complexes (CORUM database) featuring XBP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring XBP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0030968 endoplasmic reticulum unfolded protein response Database 1.35
Category members GO Category GO:0006987 activation of signaling protein activity involved in unfolded protein response Database 1.26
Category members GO Category GO:0006955 immune response Database 1.22
Category members Pathway Pathway_147 REACTOME_UNFOLDED_PROTEIN_RESPONSE 0 1.08
Category members Pathway Pathway_185 PID_ERA_GENOMIC_PATHWAY 0 1.05
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members GO Category GO:0042493 response to drug Database 0.66
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members Pathway Pathway_146 REACTOME_DIABETES_PATHWAYS 0 0.39
Category members Pathway Pathway_916 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA 0 0.33
Category members Pathway Pathway_915 REACTOME_ACTIVATION_OF_CHAPERONES_BY_ATF6_ALPHA 0 0.31
Category members GO Category GO:0051602 response to electrical stimulus Database 0.22
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18
Category members Pathway Pathway_148 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S 0 0.11
Category members Pathway Pathway_186 PID_HNF3A_PATHWAY 0 0
Category members GO Category GO:0002070 epithelial cell maturation Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0031017 exocrine pancreas development Database 0
Category members GO Category GO:0071236 cellular response to antibiotic Database 0


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