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Query: WDTC1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
WDTC1 0 -0.647 1.210 -1.020 -0.013

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
WDTC1 Phosphorylation S511 -0.489 0.459 _KDS(ph)ISEDEMVLR_
WDTC1 Ubiquitylation K486 -0.859 -0.593 _DITAALFSK(gl)NDGEEK_
WDTC1 Ubiquitylation K493 -0.011 -0.870 _K(gl)GPGGGAPVR_
WDTC1 Ubiquitylation K492 -0.011 -2.040 _NDGEEK(gl)KGPGGGAPVR_

Background Information for WDTC1:


Pubmed-WDTC1 »
Uniprot-WDTC1 »
Biogrid-WDTC1 »
ProteomicsDB-WDTC1 »

Tumorportal-WDTC1 »
COSMIC-WDTC1 »
GenomeRNAi-WDTC1 »
Genecards-WDTC1


Protein-protein Interactions for WDTC1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait 3-Sep Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ARHGAP44 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BCKDK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCT7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPS11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC25A22 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDTC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in WDTC1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WD40_repeat_dom IPR017986 1.39
Category members TPR-contain_dom IPR013026 0.97
Category members TPR_repeat IPR019734 0.93
Category members WD40_repeat IPR001680 0.52


Protein complexes (CORUM database) featuring WDTC1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring WDTC1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0042393 histone binding Database 0.94
Category members GO Category GO:0032869 cellular response to insulin stimulus Database 0.63
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0006006 glucose metabolic process Database 0.28
Category members GO Category GO:0001701 in utero embryonic development Database 0.2
Category members GO Category GO:0042826 histone deacetylase binding Database 0.16
Category members GO Category GO:0008361 regulation of cell size Database 0.06
Category members GO Category GO:0035264 multicellular organism growth Database 0.04
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members GO Category GO:0045717 negative regulation of fatty acid biosynthetic process Database 0.02
Category members GO Category GO:0004857 enzyme inhibitor activity Database 0
Category members GO Category GO:0043086 negative regulation of catalytic activity Database 0


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