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Query: WDR77

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
WDR77 0 -1.614 -0.190 1.540 0.322 -0.304 0.069 0.907 -1.325

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
WDR77 Phosphorylation T5 -1.388 -1.435 _MRKET(ph)PPPLVPPAAR_

Background Information for WDR77:


Pubmed-WDR77 »
Uniprot-WDR77 »
Biogrid-WDR77 »
ProteomicsDB-WDR77 »

Tumorportal-WDR77 »
COSMIC-WDR77 »
GenomeRNAi-WDR77 »
Genecards-WDR77


Protein-protein Interactions for WDR77
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CCT3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCT4 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDK2AP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait EMC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait FBL Cat. description Hein, Mann, Cell 2015
Category members IP bait GAR1 Cat. description Hein, Mann, Cell 2015
Category members IP bait JUNB Cat. description Hein, Mann, Cell 2015
Category members IP bait PRMT5 Cat. description Hein, Mann, Cell 2015
Category members IP bait WIZ Cat. description Hein, Mann, Cell 2015
Category members IP bait CCT3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCT7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CIRBP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LSM6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR77 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in WDR77
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WD40_repeat_dom IPR017986 1.39
Category members WD40_repeat IPR001680 0.52


Protein complexes (CORUM database) featuring WDR77
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 810 FCP1-associated protein complex Database 0.1
Category members Corum 811 FCP1-associated protein complex Database 0.1
Category members Corum 2838 AR coactivator complex Database 0.06
Category members Corum 837 20S methyltransferase complex Database 0.06


Categories featuring WDR77
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_771 REACTOME_METABOLISM_OF_RNA 0 INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0016070 RNA metabolic process Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_887 REACTOME_METABOLISM_OF_NON_CODING_RNA 0 4.38
Category members Pathway Pathway_943 PID_HDAC_CLASSI_PATHWAY 0 1.08
Category members GO Category GO:0008285 negative regulation of cell proliferation Database 0.28
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0006357 regulation of transcription from RNA polymerase II promoter Database 0.19
Category members GO Category GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity Database 0.12
Category members GO Category GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development Database 0.05
Category members GO Category GO:0000387 spliceosomal snRNP assembly Database 0.04
Category members GO Category GO:0008284 positive regulation of cell proliferation Database 0
Category members GO Category GO:0034660 ncRNA metabolic process Database 0
Category members GO Category GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development Database 0


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