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Query: WDR35

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
WDR35 0 0.785 0.320 -0.150

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
WDR35 Ubiquitylation K1086 0.785 _AFGTCSK(gl)AFIK_
WDR35 Ubiquitylation K590 0.254 _VTDSTGQQVVGELLK(gl)LER_
WDR35 Ubiquitylation K51 0.094 _LETQTDDAK(gl)LR_
WDR35 Ubiquitylation K680 -0.600 _ALIEK(gl)VGIK_

Background Information for WDR35:


Pubmed-WDR35 »
Uniprot-WDR35 »
Biogrid-WDR35 »
ProteomicsDB-WDR35 »

Tumorportal-WDR35 »
COSMIC-WDR35 »
GenomeRNAi-WDR35 »
Genecards-WDR35


Protein-protein Interactions for WDR35
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AURKA Cat. description Hein, Mann, Cell 2015
Category members IP bait JUP Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF2A Cat. description Hein, Mann, Cell 2015
Category members IP bait MAD2L1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NEDD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PCNT Cat. description Hein, Mann, Cell 2015
Category members IP bait RNPS1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SGTB Cat. description Hein, Mann, Cell 2015
Category members IP bait ZNF187 Cat. description Hein, Mann, Cell 2015
Category members IP bait C11orf74 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C14orf179 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DNAJC7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IFT122 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TULP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TULP3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in WDR35
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members WD40_repeat_dom IPR017986 1.39
Category members WD40_repeat IPR001680 0.52


Protein complexes (CORUM database) featuring WDR35
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring WDR35
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0005813 centrosome Database 0.75
Category members Disease phenotype Cranioectodermal_dysplasia Cranioectodermal dysplasia Database 0.01
Category members Disease phenotype Short_rib-polydactyly_syndrome_Verma-Naumoff_type Short rib-polydactyly syndrome Verma-Naumoff type Database 0
Category members GO Category GO:0005930 axoneme Database 0
Category members GO Category GO:0005932 microtubule basal body Database 0
Category members GO Category GO:0030991 intraciliary transport particle A Database 0
Category members GO Category GO:0042384 cilium assembly Database 0


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