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Query: WDR18

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
WDR18 0 -0.092 0.040 0.190 0.367 -0.599 0.724 0.276 0.222

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
WDR18 Ubiquitylation K301 -0.358 -0.546 _LWDVQSK(gl)QCIR_
WDR18 Ubiquitylation K432 -0.879 _FITRPAK(gl)_
WDR18 Ubiquitylation K263 -1.286 _SFHPEQDAGK(gl)VFK_

Background Information for WDR18:


Pubmed-WDR18 »
Uniprot-WDR18 »
Biogrid-WDR18 »
ProteomicsDB-WDR18 »

Tumorportal-WDR18 »
COSMIC-WDR18 »
GenomeRNAi-WDR18 »
Genecards-WDR18


Protein-protein Interactions for WDR18
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait EIF3I Cat. description Hein, Mann, Cell 2015
Category members IP bait EXOSC4 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF2C Cat. description Hein, Mann, Cell 2015
Category members IP bait NPM1 Cat. description Hein, Mann, Cell 2015
Category members IP bait WDR18 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in WDR18
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WD40_repeat_dom IPR017986 1.39
Category members Quinonprotein_ADH-like_supfam IPR011047 0.56
Category members WD40_repeat IPR001680 0.52
Category members G-protein_beta_WD-40_rep IPR020472 0.12


Protein complexes (CORUM database) featuring WDR18
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring WDR18
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0007275 multicellular organismal development Database 0.31


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