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Query: WDR12

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
WDR12 0 -0.032 0.150 -0.420 -1.387 -0.346

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
WDR12 Ubiquitylation K14 0.676 1.025 _FYTDNKK(gl)_
WDR12 Ubiquitylation K310 0.195 _VFNCISYSPLCK(gl)R_

Background Information for WDR12:


Pubmed-WDR12 »
Uniprot-WDR12 »
Biogrid-WDR12 »
ProteomicsDB-WDR12 »

Tumorportal-WDR12 »
COSMIC-WDR12 »
GenomeRNAi-WDR12 »
Genecards-WDR12


Protein-protein Interactions for WDR12
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CASQ2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DGCR8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IGHMBP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MKI67IP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PES1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR55 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in WDR12
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WD40_repeat_dom IPR017986 1.39
Category members WD40_repeat IPR001680 0.52
Category members NLE IPR012972 0.13
Category members G-protein_beta_WD-40_rep IPR020472 0.12


Protein complexes (CORUM database) featuring WDR12
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring WDR12
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0042273 ribosomal large subunit biogenesis Database 0.59
Category members GO Category GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Database 0.1
Category members GO Category GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Database 0.1
Category members GO Category GO:0030687 preribosome, large subunit precursor Database 0.1
Category members GO Category GO:0070545 PeBoW complex Database 0.1
Category members GO Category GO:0008283 cell proliferation Database 0.06
Category members GO Category GO:0007219 Notch signaling pathway Database 0.05
Category members GO Category GO:0043021 ribonucleoprotein complex binding Database 0


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