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Query: VPS36

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
VPS36 1 3.070 1.310 -0.830

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
VPS36 Ubiquitylation K189 1.478 1.592 _AK(gl)EMVELSK_

Background Information for VPS36:


Pubmed-VPS36 »
Uniprot-VPS36 »
Biogrid-VPS36 »
ProteomicsDB-VPS36 »

Tumorportal-VPS36 »
COSMIC-VPS36 »
GenomeRNAi-VPS36 »
Genecards-VPS36


Protein-protein Interactions for VPS36
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait SNF8 Cat. description Hein, Mann, Cell 2015
Category members IP bait VPS25 Cat. description Hein, Mann, Cell 2015
Category members IP bait KDELR1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC25A41 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VPS36 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in VPS36
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members EAP30 IPR007286 0


Protein complexes (CORUM database) featuring VPS36
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1187 ESCRT-II complex Database 0


Categories featuring VPS36
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0015031 protein transport Database 3.48
Category members Pathway Pathway_666 KEGG_ENDOCYTOSIS 0 1.25
Category members GO Category GO:0043130 ubiquitin binding Database 1.22
Category members Pathway Pathway_474 REACTOME_MEMBRANE_TRAFFICKING 0 1.14
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0016197 endosomal transport Database 0.43
Category members GO Category GO:0005768 endosome Database 0.29
Category members GO Category GO:0005770 late endosome Database 0.09
Category members Pathway Pathway_800 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT 0 0.06
Category members GO Category GO:0005764 lysosome Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0032266 phosphatidylinositol-3-phosphate binding Database 0


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