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Query: VPS25

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
VPS25 0 0.252 1.140 -0.380

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
VPS25 Ubiquitylation K92 -0.408 -0.002 _KGNLEWLDK(gl)SK_
VPS25 Ubiquitylation K94 0.254 -0.002 _GNLEWLDKSK(gl)_

Background Information for VPS25:


Pubmed-VPS25 »
Uniprot-VPS25 »
Biogrid-VPS25 »
ProteomicsDB-VPS25 »

Tumorportal-VPS25 »
COSMIC-VPS25 »
GenomeRNAi-VPS25 »
Genecards-VPS25


Protein-protein Interactions for VPS25
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait VPS25 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIFAP3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VPS36 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in VPS25
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring VPS25
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1187 ESCRT-II complex Database 0


Categories featuring VPS25
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members Pathway Pathway_666 KEGG_ENDOCYTOSIS 0 1.25
Category members Pathway Pathway_474 REACTOME_MEMBRANE_TRAFFICKING 0 1.14
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0016197 endosomal transport Database 0.43
Category members Pathway Pathway_800 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT 0 0.06
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0010008 endosome membrane Database 0


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