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Query: USP48

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
USP48 2 5.563 1.640 -0.790 0.092 0.098 0.144 0.339
USP48 2 5.563 1.640 -0.790 -1.135

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
USP48 Ubiquitylation K550 2.800 3.226 _LTVK(gl)ALCK_
USP48 Ubiquitylation K554 1.825 _ALCK(gl)ECVVER_
USP48 Ubiquitylation K708 0.593 1.125 _ECCSQCK(gl)ILER_
USP48 Ubiquitylation K586 1.311 0.666 _AAVK(gl)GSDGFWVGK_
USP48 Ubiquitylation K276 0.406 _YFCENCQSK(gl)QNATR_
USP48 Ubiquitylation K701 0.362 0.328 _APEFPSYK(gl)ECCSQCK_
USP48 Ubiquitylation K681 0.985 0.290 _LVSK(gl)EAWSK_
USP48 Ubiquitylation K231 0.479 -0.168 _ESK(gl)LLSK_
USP48 Ubiquitylation K9 -0.077 -0.446 _LQLEK(gl)AAWR_
USP48 Ubiquitylation K258 1.357 _QLTDCISEFLK(gl)EEK_

Background Information for USP48:


Pubmed-USP48 »
Uniprot-USP48 »
Biogrid-USP48 »
ProteomicsDB-USP48 »

Tumorportal-USP48 »
COSMIC-USP48 »
GenomeRNAi-USP48 »
Genecards-USP48


Protein-protein Interactions for USP48
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait HIST1H2BJ Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NR1D2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait USP48 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF232 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in USP48
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ubiquitin-rel_dom IPR029071 1.79
Category members Ubiquitin-like IPR000626 1.61
Category members UCH/PAN2 IPR028889 0.62
Category members Peptidase_C19_UCH IPR001394 0.53
Category members Pept_C19_DUSP IPR006615 0.23


Protein complexes (CORUM database) featuring USP48
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring USP48
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0006511 ubiquitin-dependent protein catabolic process Database 3.57
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0004221 ubiquitin thiolesterase activity Database 1.36
Category members GO Category GO:0008234 cysteine-type peptidase activity Database 0


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