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Query: USP42

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
USP42 0 0.751 0.050 -0.340
USP42 0 0.751 0.050 -0.340 -1.459 0.532

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
USP42 Phosphorylation S1181 0.385 0.937 _RS(ph)EQKDPLEEPK_
USP42 Phosphorylation S856 -0.784 -1.241 _DSALAEAPEGLS(ph)PAPPAR_
USP42 Phosphorylation S754 -0.957 -1.243 _DAEPQPGS(ph)PAAESLEEPDAAAGLSSTK_
USP42 Phosphorylation S75 -1.609 -1.482 _SKPS(ph)PQKDQALGDGIAPPQK_
USP42 Ubiquitylation K279 0.356 _ALEQFVK(gl)PEQLDGENSYK_
USP42 Ubiquitylation K327 0.355 _FANFTGGK(gl)IAK_
USP42 Ubiquitylation K330 0.226 _FANFTGGKIAK(gl)_

Background Information for USP42:





Protein-protein Interactions for USP42

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MAD2L2 Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP6C Cat. description Hein, Mann, Cell 2015
Category members IP bait JMJD6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in USP42

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members UCH/PAN2 IPR028889 0.62
Category members Peptidase_C19_UCH IPR001394 0.53


Protein complexes (CORUM database) featuring USP42

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring USP42

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0006511 ubiquitin-dependent protein catabolic process Database 3.57
Category members GO Category GO:0004843 ubiquitin-specific protease activity Database 3.28
Category members GO Category GO:0004221 ubiquitin thiolesterase activity Database 1.36
Category members GO Category GO:0016579 protein deubiquitination Database 1.32
Category members GO Category GO:0030154 cell differentiation Database 0.06
Category members GO Category GO:0007283 spermatogenesis Database 0


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