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Query: USP36

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
USP36 1 3.784 -0.180 0.260 0.221 0.341

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
USP36 Phosphorylation S713 1.535 _ATGNDLRPPPPS(ph)PSSDLTHPMK_
USP36 Ubiquitylation K338 0.690 0.945 _FANFSGGK(gl)ITK_
USP36 Ubiquitylation K341 0.923 _FANFSGGKITK(gl)_
USP36 Phosphorylation T581 0.384 _DVVLST(ph)SPK_
USP36 Phosphorylation S582 -0.208 0.145 _DVVLSTS(ph)PK_
USP36 Phosphorylation S952 -1.261 -0.561 _HSCSPMGDGDPEAMEES(ph)PR_

Background Information for USP36:





Protein-protein Interactions for USP36

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait HNRNPU Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015
Category members IP bait NT5E Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait USP36 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in USP36

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members UCH/PAN2 IPR028889 0.62
Category members Peptidase_C19_UCH IPR001394 0.53


Protein complexes (CORUM database) featuring USP36

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring USP36

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members DDR Literature pubmedid:TBD1_UV_decreased Elia et al, 2015 UV decreased acetylation events Elia et al. 10.54
Category members GO Category GO:0006511 ubiquitin-dependent protein catabolic process Database 3.57
Category members GO Category GO:0004221 ubiquitin thiolesterase activity Database 1.36
Category members GO Category GO:0008234 cysteine-type peptidase activity Database 0


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