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Query: URI1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
URI1 0 1.217 0.510 -0.740

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
URI1 Phosphorylation S442 0.809 0.123 _SIS(ph)CEEATCSDTSESILEEEPQENQKK_
URI1 Phosphorylation S440 -0.055 _S(ph)ISCEEATCSDTSESILEEEPQENQK_
URI1 Phosphorylation T5 -0.345 _(ac)MEAPT(ph)VETPPDPSPPSAPAPALVPLR_
URI1 Phosphorylation S372 1.094 -0.365 _KNS(ph)TGSGHSAQELPTIR_

Background Information for URI1:


Pubmed-URI1 »
Uniprot-URI1 »
Biogrid-URI1 »
ProteomicsDB-URI1 »

Tumorportal-URI1 »
COSMIC-URI1 »
GenomeRNAi-URI1 »
Genecards-URI1


Protein-protein Interactions for URI1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PFDN2 Cat. description Hein, Mann, Cell 2015
Category members IP bait POLR1A Cat. description Hein, Mann, Cell 2015
Category members IP bait POLR3E Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP1CB Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP1CC Cat. description Hein, Mann, Cell 2015
Category members IP bait RUVBL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RUVBL2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SEPT9 Cat. description Hein, Mann, Cell 2015


Protein Domains in URI1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Prefoldin_subunit_alpha IPR004127 0
Category members Prefoldin IPR009053 0


Protein complexes (CORUM database) featuring URI1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 781 URI complex (Unconventional prefoldin RPB5 Interactor) Database 0.77


Categories featuring URI1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members GO Category GO:0006457 protein folding Database 4.93
Category members GO Category GO:0051082 unfolded protein binding Database 3.74
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0005665 DNA-directed RNA polymerase II, core complex Database 0.38
Category members GO Category GO:0030425 dendrite Database 0.26
Category members GO Category GO:0006357 regulation of transcription from RNA polymerase II promoter Database 0.19
Category members GO Category GO:0016272 prefoldin complex Database 0.15
Category members GO Category GO:0071383 cellular response to steroid hormone stimulus Database 0.08
Category members GO Category GO:0001106 RNA polymerase II transcription corepressor activity Database 0.06
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members GO Category GO:0001558 regulation of cell growth Database 0
Category members GO Category GO:0004864 protein phosphatase inhibitor activity Database 0
Category members GO Category GO:0009615 response to virus Database 0
Category members GO Category GO:0010923 negative regulation of phosphatase activity Database 0
Category members GO Category GO:0071363 cellular response to growth factor stimulus Database 0


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