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Query: UHRF2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
UHRF2 0 1.801 -0.640 0.600 0.561 0.402
UHRF2 0 1.801 -0.640 0.600 0.592 -0.256 0.358 0.108 0.276

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
UHRF2 Ubiquitylation K573 -0.456 _YDGIYK(gl)VVK_

Background Information for UHRF2:





Protein-protein Interactions for UHRF2

Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in UHRF2

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ubiquitin-rel_dom IPR029071 1.79
Category members Ubiquitin-like IPR000626 1.61
Category members Znf_FYVE_PHD IPR011011 1.23
Category members Znf_PHD IPR001965 1.15
Category members Znf_PHD-finger IPR019787 0.91
Category members Znf_RING IPR001841 0


Protein complexes (CORUM database) featuring UHRF2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring UHRF2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0006511 ubiquitin-dependent protein catabolic process Database 3.57
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0005720 nuclear heterochromatin Database 1.41
Category members GO Category GO:0042393 histone binding Database 0.94
Category members GO Category GO:0007049 cell cycle Database 0.69
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members GO Category GO:0051865 protein autoubiquitination Database 0.18
Category members GO Category GO:0051726 regulation of cell cycle Database 0.11
Category members GO Category GO:0071158 positive regulation of cell cycle arrest Database 0.11
Category members GO Category GO:0016567 protein ubiquitination Database 0.07
Category members GO Category GO:0008283 cell proliferation Database 0.06
Category members GO Category GO:0030154 cell differentiation Database 0.06


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