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Query: UBE2O

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
UBE2O 0 3.330 -0.370 -0.040

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
UBE2O Ubiquitylation K865 0.875 1.470 _LQENLK(gl)K_
UBE2O Ubiquitylation K815 1.051 1.313 _ELK(gl)EAIK_
UBE2O Phosphorylation S839 0.693 0.156 _NMTVEQLLTGSPTS(ph)PTVEPEKPTR_
UBE2O Phosphorylation S896 -0.467 0.090 _KEDKPEGQS(ph)PVK_
UBE2O Phosphorylation S401 -0.086 0.001 _IMSCS(ph)PDTQCSR_
UBE2O Phosphorylation S836 -1.051 -2.096 _NM(ox)TVEQLLTGS(ph)PTSPTVEPEKPTR_
UBE2O Ubiquitylation K132 0.916 _VQWYPEGVK(gl)QHVK_
UBE2O Ubiquitylation K373 -0.160 _IAWECPEK(gl)NCAQGEGSMAK_
UBE2O Ubiquitylation K524 -0.115 _SIPLSIKNLK(gl)_
UBE2O Ubiquitylation K672 -1.366 _IGNTEDGAPHK(gl)EDEPSVGQVAR_
UBE2O Ubiquitylation K809 -0.128 _DGPPK(gl)SFR_
UBE2O Ubiquitylation K1267 0.196 _GFIK(gl)SIR_

Background Information for UBE2O:


Pubmed-UBE2O »
Uniprot-UBE2O »
Biogrid-UBE2O »
ProteomicsDB-UBE2O »

Tumorportal-UBE2O »
COSMIC-UBE2O »
GenomeRNAi-UBE2O »
Genecards-UBE2O


Protein-protein Interactions for UBE2O
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CROCC Cat. description Hein, Mann, Cell 2015
Category members IP bait GSTP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait INSR Cat. description Hein, Mann, Cell 2015
Category members IP bait ITGB3BP Cat. description Hein, Mann, Cell 2015
Category members IP bait AKAP17A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait AKT2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait AURKAIP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BMP4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC33 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLK3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait E4F1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EPB41L5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGFRL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H2BA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IFRD2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IKZF5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait JPH4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait L3MBTL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LLGL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LUC7L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LUC7L2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MDK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPL35 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NAP1L1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NOL12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL15 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL18 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRIM11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UBE2O Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WBSCR22 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZFP41 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF517 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF556 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF563 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF574 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF669 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF707 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in UBE2O
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members UBQ-conjugat_E2 IPR000608 0
Category members UBQ-conjugating_enzyme/RWD IPR016135 0


Protein complexes (CORUM database) featuring UBE2O
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring UBE2O
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members Pathway Pathway_764 REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION 0 2.56
Category members Pathway Pathway_888 KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS 0 2.22
Category members Pathway Pathway_832 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION 0 1.58
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members GO Category GO:0016881 acid-amino acid ligase activity Database 0


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