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Query: UBE2M

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
UBE2M 1 1.860 2.990 -1.120 -0.569 0.612 0.392

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
UBE2M Ubiquitylation K8 0.340 0.758 _LFSLK(gl)QQK_
UBE2M Ubiquitylation K3 0.667 0.186 _(ac)MIK(gl)LFSLK_
UBE2M Ubiquitylation K72 0.129 0.036 _LVICPDEGFYK(gl)SGK_
UBE2M Ubiquitylation K94 -0.409 -0.910 _VGQGYPHDPPKVK(gl)_
UBE2M Ubiquitylation K26 0.352 _K(gl)ASAAQLR_

Background Information for UBE2M:


Pubmed-UBE2M »
Uniprot-UBE2M »
Biogrid-UBE2M »
ProteomicsDB-UBE2M »

Tumorportal-UBE2M »
COSMIC-UBE2M »
GenomeRNAi-UBE2M »
Genecards-UBE2M


Protein-protein Interactions for UBE2M
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AP1S2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCDC22 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH13 Cat. description Hein, Mann, Cell 2015
Category members IP bait PAX6 Cat. description Hein, Mann, Cell 2015
Category members IP bait ROCK1 Cat. description Hein, Mann, Cell 2015
Category members IP bait UBE2M Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in UBE2M
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members UBQ-conjugat_E2 IPR000608 0
Category members UBQ-conjugating_enzyme/RWD IPR016135 0


Protein complexes (CORUM database) featuring UBE2M
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring UBE2M
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members Pathway Pathway_764 REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION 0 2.56
Category members Pathway Pathway_888 KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS 0 2.22
Category members Pathway Pathway_832 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION 0 1.58
Category members Pathway Pathway_185 PID_ERA_GENOMIC_PATHWAY 0 1.05
Category members Pathway Pathway_1260 PID_ERB_GENOMIC_PATHWAY 0 1.04
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members Pathway Pathway_973 BIOCARTA_P27_PATHWAY 0 0.1
Category members GO Category GO:0045116 protein neddylation Database 0.1
Category members GO Category GO:0016567 protein ubiquitination Database 0.07
Category members GO Category GO:0005575 cellular_component Database 0
Category members GO Category GO:0006464 cellular protein modification process Database 0
Category members GO Category GO:0016881 acid-amino acid ligase activity Database 0
Category members GO Category GO:0019788 NEDD8 ligase activity Database 0
Category members GO Category GO:0043525 positive regulation of neuron apoptotic process Database 0


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