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Query: UBA3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
UBA3 0 1.007 0.780 -0.920

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
UBA3 Ubiquitylation K307 0.013 0.773 _LTQGVVK(gl)R_
UBA3 Ubiquitylation K409 0.234 _SPAITATLEGK(gl)NR_

Background Information for UBA3:


Pubmed-UBA3 »
Uniprot-UBA3 »
Biogrid-UBA3 »
ProteomicsDB-UBA3 »

Tumorportal-UBA3 »
COSMIC-UBA3 »
GenomeRNAi-UBA3 »
Genecards-UBA3


Protein-protein Interactions for UBA3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait APIP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UBE2M Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZBTB44 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in UBA3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ThiF_NAD_FAD-bd IPR000594 0.19
Category members Molybdenum_cofac_synth_MoeB IPR009036 0.19
Category members UBact_repeat IPR000127 0.08
Category members Ubiquitin-activating_enzyme IPR019572 0.08


Protein complexes (CORUM database) featuring UBA3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2162 APPBP1-UBA3 complex Database 0.04


Categories featuring UBA3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members Pathway Pathway_764 REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION 0 2.56
Category members Pathway Pathway_888 KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS 0 2.22
Category members Pathway Pathway_832 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION 0 1.58
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members Pathway Pathway_185 PID_ERA_GENOMIC_PATHWAY 0 1.05
Category members Pathway Pathway_1260 PID_ERB_GENOMIC_PATHWAY 0 1.04
Category members GO Category GO:0016922 ligand-dependent nuclear receptor binding Database 0.89
Category members Pathway Pathway_880 PID_AR_PATHWAY 0 0.58
Category members GO Category GO:0046982 protein heterodimerization activity Database 0.28
Category members GO Category GO:0008641 small protein activating enzyme activity Database 0.26
Category members GO Category GO:0051726 regulation of cell cycle Database 0.11
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members GO Category GO:0045116 protein neddylation Database 0.1
Category members GO Category GO:0019781 NEDD8 activating enzyme activity Database 0.04
Category members GO Category GO:0006464 cellular protein modification process Database 0
Category members GO Category GO:0006508 proteolysis Database 0
Category members GO Category GO:0007113 endomitotic cell cycle Database 0
Category members GO Category GO:0016881 acid-amino acid ligase activity Database 0


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