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bioLOGIC Data

Query: TWF1

RNAi screen result	RNAPII IP (PI)	CSB IP	CSB IP (PI)	Chrom.	Chrom. (PI)	Phosphorylation	Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:
Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen

Gene name	Point score	Z-score sums	RNAi high	RNAi low	RNAPII-IP (PI)	CSB-IP	CSB-IP (PI)	Chrom.	Chrom. (PI)
TWF1	1	2.959	0.880	-0.820				0.384

PTM Sites:
Back to Protein Results | Red/green: hit at lower/upper end of the respective screen

Gene name	PTM type	PTM site	UV	UV (PI)	Sequence
TWF1	Phosphorylation	S143	1.600	0.975	_YLLSQSS(ph)PAPLTAAEEELR_

Background Information for TWF1:

Pubmed-TWF1 »

Uniprot-TWF1 »

Biogrid-TWF1 »

ProteomicsDB-TWF1 »

Tumorportal-TWF1 »

COSMIC-TWF1 »

GenomeRNAi-TWF1 »

Genecards-TWF1

Protein-protein Interactions for TWF1

Show screen data for	Category Name and Description	Link to cat description	Data Source
Category members	IP bait ACTB	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait ANLN	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait CALML3	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait CAPZA2	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait CORO1C	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait DBN1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait FLNA	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait FLOT2	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait IQGAP1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait LIMA1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait MYH9	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait MYO18A	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait MYO19	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait MYO1C	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait PPP1CB	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait PRICKLE3	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait SYNPO	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait TMOD3	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait TPM1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait BCL7C	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait TWF1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015

Protein Domains in TWF1

	Domain name	Domain Description	TC-NER relevance -log10(p-value)
Category members	ADF-H	IPR002108	0.83

Protein complexes (CORUM database) featuring TWF1

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)

Categories featuring TWF1

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	GO Category	GO:0005737	cytoplasm	Database	12.81
Category members	GO Category	GO:0005524	ATP binding	Database	5.54
Category members	GO Category	GO:0003779	actin binding	Database	5.41
Category members	GO Category	GO:0015629	actin cytoskeleton	Database	2.22
Category members	GO Category	GO:0005911	cell-cell junction	Database	1.4
Category members	GO Category	GO:0032587	ruffle membrane	Database	0.65
Category members	GO Category	GO:0048471	perinuclear region of cytoplasm	Database	0.39
Category members	GO Category	GO:0005622	intracellular	Database	0.32
Category members	GO Category	GO:0051016	barbed-end actin filament capping	Database	0.21
Category members	GO Category	GO:0030837	negative regulation of actin filament polymerization	Database	0.13
Category members	GO Category	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	Database	0.09
Category members	GO Category	GO:0030175	filopodium	Database	0.05
Category members	GO Category	GO:0004713	protein tyrosine kinase activity	Database	0.01
Category members	GO Category	GO:0003785	actin monomer binding	Database	0
Category members	GO Category	GO:0030016	myofibril	Database	0
Category members	GO Category	GO:0042989	sequestering of actin monomers	Database	0