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Query: TUBB

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TUBB 0 0.053 0.280 -0.330 -0.769 -0.098 0.204 0.142 -0.012

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TUBB Ubiquitylation K58 -0.451 0.939 _ISVYYNEATGGK(gl)YVPR_

Background Information for TUBB:


Pubmed-TUBB »
Uniprot-TUBB »
Biogrid-TUBB »
ProteomicsDB-TUBB »

Tumorportal-TUBB »
COSMIC-TUBB »
GenomeRNAi-TUBB »
Genecards-TUBB


Protein-protein Interactions for TUBB
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ARMC6 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCT2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCT3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCT7 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCT8 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPF Cat. description Hein, Mann, Cell 2015
Category members IP bait KCTD5 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAD2L1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NEK9 Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP6R1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SORT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TRIM29 Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBA1C Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBA3C;TUBA3E Cat. description Hein, Mann, Cell 2015
Category members IP bait CDK13 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EFHA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EML1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TUBB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TUBB2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UQCRH Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TUBB
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Tubulin IPR000217 0
Category members Alpha_tubulin IPR002452 0
Category members Beta_tubulin IPR002453 0
Category members Gamma_tubulin IPR002454 0
Category members Delta_tubulin IPR002967 0
Category members Tubulin_FtsZ_GTPase IPR003008 0
Category members Epsilon_tubulin IPR004057 0
Category members Tub_FtsZ_C IPR008280 0
Category members Tubulin/FtsZ_2-layer-sand-dom IPR018316 0
Category members Misato_II_tubulin-like IPR019605 0


Protein complexes (CORUM database) featuring TUBB
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1335 SNW1 complex Database 3.59
Category members Corum 1400 ASCOM complex Database 0


Categories featuring TUBB
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members GO Category GO:0043234 protein complex Database 2.73
Category members GO Category GO:0070062 extracellular vesicular exosome Database 1.36
Category members GO Category GO:0015630 microtubule cytoskeleton Database 1.34
Category members GO Category GO:0005874 microtubule Database 1.21
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0051301 cell division Database 1.15
Category members GO Category GO:0005198 structural molecule activity Database 0.94
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0032403 protein complex binding Database 0.49
Category members Pathway Pathway_727 REACTOME_MITOTIC_G2_G2_M_PHASES 0 0.46
Category members Pathway Pathway_1026 KEGG_PATHOGENIC_ESCHERICHIA_COLI_INFECTION 0 0.45
Category members Pathway Pathway_728 REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES 0 0.4
Category members Pathway Pathway_730 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES 0 0.33
Category members GO Category GO:0000086 G2/M transition of mitotic cell cycle Database 0.33
Category members GO Category GO:0007017 microtubule-based process Database 0.3
Category members GO Category GO:0006184 GTP catabolic process Database 0.29
Category members GO Category GO:0051225 spindle assembly Database 0.25
Category members GO Category GO:0006928 cellular component movement Database 0.24
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members GO Category GO:0003924 GTPase activity Database 0.16
Category members GO Category GO:0030705 cytoskeleton-dependent intracellular transport Database 0.13
Category members Pathway Pathway_213 KEGG_GAP_JUNCTION 0 0.11
Category members GO Category GO:0042267 natural killer cell mediated cytotoxicity Database 0.02
Category members GO Category GO:0005200 structural constituent of cytoskeleton Database 0
Category members GO Category GO:0005641 nuclear envelope lumen Database 0
Category members GO Category GO:0009987 cellular process Database 0
Category members GO Category GO:0042288 MHC class I protein binding Database 0
Category members GO Category GO:0044297 cell body Database 0
Category members GO Category GO:0051258 protein polymerization Database 0


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