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Query: TUBA1C

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TUBA1C 1 3.432 0.742 -0.126 0.853 0.585
TUBA1C 1 3.432 0.217 0.208 1.746

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for TUBA1C:


Pubmed-TUBA1C »
Uniprot-TUBA1C »
Biogrid-TUBA1C »
ProteomicsDB-TUBA1C »

Tumorportal-TUBA1C »
COSMIC-TUBA1C »
GenomeRNAi-TUBA1C »
Genecards-TUBA1C


Protein-protein Interactions for TUBA1C
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait IMMT Cat. description Hein, Mann, Cell 2015
Category members IP bait MIB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait NEK9 Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBA1C Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBG1 Cat. description Hein, Mann, Cell 2015
Category members IP bait C1orf85 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TPSB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TUBA1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TXNDC9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VAPA Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TUBA1C
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Tubulin IPR000217 0
Category members Alpha_tubulin IPR002452 0
Category members Beta_tubulin IPR002453 0
Category members Delta_tubulin IPR002967 0
Category members Tubulin_FtsZ_GTPase IPR003008 0
Category members Epsilon_tubulin IPR004057 0
Category members Tub_FtsZ_C IPR008280 0
Category members Tubulin/FtsZ_2-layer-sand-dom IPR018316 0


Protein complexes (CORUM database) featuring TUBA1C
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TUBA1C
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0006457 protein folding Database 4.93
Category members GO Category GO:0043234 protein complex Database 2.73
Category members GO Category GO:0019904 protein domain specific binding Database 1.85
Category members GO Category GO:0015630 microtubule cytoskeleton Database 1.34
Category members GO Category GO:0005874 microtubule Database 1.21
Category members GO Category GO:0051301 cell division Database 1.15
Category members GO Category GO:0005198 structural molecule activity Database 0.94
Category members Pathway Pathway_742 REACTOME_PROTEIN_FOLDING 0 0.9
Category members GO Category GO:0051084 'de novo' posttranslational protein folding Database 0.63
Category members GO Category GO:0000226 microtubule cytoskeleton organization Database 0.5
Category members Pathway Pathway_1026 KEGG_PATHOGENIC_ESCHERICHIA_COLI_INFECTION 0 0.45
Category members Pathway Pathway_1288 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC 0 0.4
Category members Pathway Pathway_54 BIOCARTA_MTA3_PATHWAY 0 0.36
Category members GO Category GO:0007017 microtubule-based process Database 0.3
Category members GO Category GO:0006184 GTP catabolic process Database 0.29
Category members GO Category GO:0071353 cellular response to interleukin-4 Database 0.19
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members GO Category GO:0003924 GTPase activity Database 0.16
Category members GO Category GO:0030705 cytoskeleton-dependent intracellular transport Database 0.13
Category members Pathway Pathway_213 KEGG_GAP_JUNCTION 0 0.11
Category members Pathway Pathway_1296 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC 0 0.08
Category members Pathway Pathway_1295 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY 0 0.07
Category members GO Category GO:0005881 cytoplasmic microtubule Database 0.04
Category members GO Category GO:0005200 structural constituent of cytoskeleton Database 0
Category members GO Category GO:0051258 protein polymerization Database 0


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