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Query: TTF1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TTF1 0 -1.298 -0.858 -0.752

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TTF1 Ubiquitylation K765 0.657 _AK(gl)VSLIER_
TTF1 Phosphorylation S65 -0.298 -0.047 _DFQHLISS(ph)PLKK_
TTF1 Phosphorylation S487 -1.206 -0.120 _YLSADSGDADDS(ph)DADLGSAVK_

Background Information for TTF1:


Pubmed-TTF1 »
Uniprot-TTF1 »
Biogrid-TTF1 »
ProteomicsDB-TTF1 »

Tumorportal-TTF1 »
COSMIC-TTF1 »
GenomeRNAi-TTF1 »
Genecards-TTF1


Protein-protein Interactions for TTF1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait GPSM2 Cat. description Hein, Mann, Cell 2015
Category members IP bait L3MBTL2 Cat. description Hein, Mann, Cell 2015
Category members IP bait NLRP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait RNASEH2A Cat. description Hein, Mann, Cell 2015
Category members IP bait VPS26B Cat. description Hein, Mann, Cell 2015
Category members IP bait CNBP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DGCR8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPATCH4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H1T Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRR11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBM34 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL14 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL18A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL30 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL37A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPS14 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR46 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TTF1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members SANT/Myb IPR001005 2.18
Category members Myb-like_dom IPR017877 0.63
Category members Homeodomain-like IPR009057 0


Protein complexes (CORUM database) featuring TTF1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TTF1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members GO Category GO:0006338 chromatin remodeling Database 4.95
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0006360 transcription from RNA polymerase I promoter Database 2.66
Category members GO Category GO:0006361 transcription initiation from RNA polymerase I promoter Database 2.41
Category members GO Category GO:0006363 termination of RNA polymerase I transcription Database 1.71
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006353 DNA-dependent transcription, termination Database 0.26
Category members GO Category GO:0008156 negative regulation of DNA replication Database 0.03
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0


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