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Query: TTC1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TTC1 0 1.203 0.360 -0.600

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TTC1 Ubiquitylation K180 0.919 _EMAINDCSK(gl)AIQLNPSYIR_
TTC1 Ubiquitylation K244 -0.337 0.833 _LK(gl)EEMLGK_
TTC1 Ubiquitylation K152 -0.493 0.277 _ALEMCPSCFQK(gl)ER_
TTC1 Phosphorylation T21 0.203 _VT(ph)DTQEAECAGPPVPDPK_
TTC1 Phosphorylation T23 0.037 _VTDT(ph)QEAECAGPPVPDPK_
TTC1 Ubiquitylation K250 0.081 _LKEEMLGK(gl)LK_
TTC1 Ubiquitylation K252 -0.469 _LKEEMLGKLK(gl)_

Background Information for TTC1:


Pubmed-TTC1 »
Uniprot-TTC1 »
Biogrid-TTC1 »
ProteomicsDB-TTC1 »

Tumorportal-TTC1 »
COSMIC-TTC1 »
GenomeRNAi-TTC1 »
Genecards-TTC1


Protein-protein Interactions for TTC1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BAG3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CBX4 Cat. description Hein, Mann, Cell 2015
Category members IP bait CBX7 Cat. description Hein, Mann, Cell 2015
Category members IP bait EEF1A1;EEF1A1P5 Cat. description Hein, Mann, Cell 2015
Category members IP bait HIF1A Cat. description Hein, Mann, Cell 2015
Category members IP bait HSP90AA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NAA11 Cat. description Hein, Mann, Cell 2015
Category members IP bait PTPN13 Cat. description Hein, Mann, Cell 2015
Category members IP bait QSOX2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SIKE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TRIP11 Cat. description Hein, Mann, Cell 2015
Category members IP bait VAPA Cat. description Hein, Mann, Cell 2015
Category members IP bait LIMK2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCCA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SETDB1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPSB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SRPRB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SYT11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TTC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VAPA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VAPB Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TTC1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members TPR_1 IPR001440 1.39
Category members TPR-contain_dom IPR013026 0.97
Category members TPR_repeat IPR019734 0.93


Protein complexes (CORUM database) featuring TTC1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TTC1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0006457 protein folding Database 4.93
Category members GO Category GO:0051082 unfolded protein binding Database 3.74
Category members GO Category GO:0005778 peroxisomal membrane Database 0.01


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