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Query: TSR1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TSR1 1 4.448 -0.280 0.370 -0.565 2.336 0.012

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TSR1 Ubiquitylation K72 0.299 0.937 _EAVLAEK(gl)R_
TSR1 Ubiquitylation K771 -1.356 _SQDTVLMNLYK(gl)R_
TSR1 Ubiquitylation K38 1.357 _LALK(gl)TLSK_

Background Information for TSR1:





Protein-protein Interactions for TSR1

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDK2AP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CENPQ Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP78 Cat. description Hein, Mann, Cell 2015
Category members IP bait EIF3A Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPU Cat. description Hein, Mann, Cell 2015
Category members IP bait IBTK Cat. description Hein, Mann, Cell 2015
Category members IP bait NOP56 Cat. description Hein, Mann, Cell 2015
Category members IP bait NPM1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL35 Cat. description Hein, Mann, Cell 2015
Category members IP bait RRBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SRP72 Cat. description Hein, Mann, Cell 2015
Category members IP bait TSR1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZBTB48 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TSR1

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members BMS1_TSR1_C IPR007034 0.31
Category members AARP2CN IPR012948 0.31
Category members Transl_B-barrel IPR009000 0.24


Protein complexes (CORUM database) featuring TSR1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TSR1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0042255 ribosome assembly Database 1.46
Category members GO Category GO:0042254 ribosome biogenesis Database 0.29


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