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Query: TRIM27

This is a cancer-associated gene according to the Sanger cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TRIM27 0 -3.246 -0.050 -0.720 -1.413 0.009 -0.056 -0.923 -0.972

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TRIM27 Ubiquitylation K304 -0.464 -0.023 _MQSDMEK(gl)IQELR_
TRIM27 Ubiquitylation K297 -0.084 _QFTEK(gl)MQSDMEK_
TRIM27 Ubiquitylation K382 0.132 _HYWEVEVGDKAK(gl)_

Background Information for TRIM27:





Protein-protein Interactions for TRIM27

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BCOR Cat. description Hein, Mann, Cell 2015
Category members IP bait CD2AP Cat. description Hein, Mann, Cell 2015
Category members IP bait CDC23 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP135 Cat. description Hein, Mann, Cell 2015
Category members IP bait ELMSAN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait GPKOW Cat. description Hein, Mann, Cell 2015
Category members IP bait HMG20A Cat. description Hein, Mann, Cell 2015
Category members IP bait KPNA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAD2L1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MLLT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NEDD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PCGF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PEO1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PRKAA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RACGAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RANBP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait RING1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RNF2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SLAIN2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TAF15 Cat. description Hein, Mann, Cell 2015
Category members IP bait TCEAL4 Cat. description Hein, Mann, Cell 2015
Category members IP bait TCF20 Cat. description Hein, Mann, Cell 2015
Category members IP bait TINF2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMED2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TRIM29 Cat. description Hein, Mann, Cell 2015
Category members IP bait TSNAX Cat. description Hein, Mann, Cell 2015
Category members IP bait USP11 Cat. description Hein, Mann, Cell 2015
Category members IP bait USP7 Cat. description Hein, Mann, Cell 2015
Category members IP bait C1orf106 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GLTSCR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IKZF5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KRBA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAP7D2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NDEL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait POTEB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRIM27 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF219 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF621 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF764 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF785 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TRIM27

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_B-box_chordata IPR020457 0.37
Category members Znf_B-box IPR000315 0
Category members Znf_RING IPR001841 0
Category members Znf_C3HC4_RING-type IPR018957 0


Protein complexes (CORUM database) featuring TRIM27

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5663 TRIM27-RB1 complex Database 0


Categories featuring TRIM27

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members Human mutations Sanger_cancer_genes Sanger cancer genes Database 4.88
Category members Disease phenotype THYROID_CARCINOMA_PAPILLARY THYROID CARCINOMA PAPILLARY Database 0.72
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0046872 metal ion binding Database 0


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