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Query: TRIM2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TRIM2 0 1.786 0.110 0.320

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TRIM2 Phosphorylation S455 0.615 0.851 _SADVS(ph)PTTEGVK_
TRIM2 Phosphorylation S37 -0.298 0.216 _(ac)ASEGTNIPS(ph)PVVR_

Background Information for TRIM2:


Pubmed-TRIM2 »
Uniprot-TRIM2 »
Biogrid-TRIM2 »
ProteomicsDB-TRIM2 »

Tumorportal-TRIM2 »
COSMIC-TRIM2 »
GenomeRNAi-TRIM2 »
Genecards-TRIM2


Protein-protein Interactions for TRIM2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait NUFIP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRIM2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TRIM2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Bbox_C IPR003649 0.18
Category members Filamin/ABP280_rpt IPR001298 0.02
Category members Filamin/ABP280_repeat-like IPR017868 0
Category members Znf_B-box IPR000315 0
Category members NHL_repeat IPR001258 0
Category members Znf_RING IPR001841 0
Category members NHL_repeat_subgr IPR013017 0
Category members Ig_E-set IPR014756 0
Category members Znf_C3HC4_RING-type IPR018957 0


Protein complexes (CORUM database) featuring TRIM2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TRIM2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members GO Category GO:0043523 regulation of neuron apoptotic process Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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