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Query: TRERF1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TRERF1 0 0.350

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TRERF1 Phosphorylation S540 0.361 -0.011 _AS(ph)PNLKQEEGEK_
TRERF1 Phosphorylation S778 -1.172 -0.181 _SNS(ph)IDGSNVTVTPGPGEQTVDVEPR_
TRERF1 Phosphorylation S782 -0.630 -0.674 _SNSIDGS(ph)NVTVT(ph)PGPGEQTVDVEPR_
TRERF1 Phosphorylation T787 -0.901 -0.736 _SNSIDGS(ph)NVTVT(ph)PGPGEQTVDVEPR_

Background Information for TRERF1:


Pubmed-TRERF1 »
Uniprot-TRERF1 »
Biogrid-TRERF1 »
ProteomicsDB-TRERF1 »

Tumorportal-TRERF1 »
COSMIC-TRERF1 »
GenomeRNAi-TRERF1 »
Genecards-TRERF1


Protein-protein Interactions for TRERF1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait HDAC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TRERF1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members SANT/Myb IPR001005 2.18
Category members Znf_C2H2-like IPR015880 1.29
Category members Znf_C2H2 IPR007087 0.92
Category members ELM2_dom IPR000949 0.51
Category members Homeodomain-like IPR009057 0


Protein complexes (CORUM database) featuring TRERF1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TRERF1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members DDR Literature pubmedid:TBD1_UV_decreased Elia et al, 2015 UV decreased acetylation events Elia et al. 10.54
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0008134 transcription factor binding Database 0.37
Category members GO Category GO:0007275 multicellular organismal development Database 0.31
Category members GO Category GO:0006694 steroid biosynthetic process Database 0.29
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity Database 0.12
Category members GO Category GO:0001104 RNA polymerase II transcription cofactor activity Database 0.08
Category members GO Category GO:0006707 cholesterol catabolic process Database 0
Category members GO Category GO:0008301 DNA binding, bending Database 0
Category members GO Category GO:0042592 homeostatic process Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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