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Query: TOR1A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TOR1A 0 -1.511 -0.270 -0.250

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TOR1A Ubiquitylation K349 -1.261 _VFSDK(gl)GCK_

Background Information for TOR1A:





Protein-protein Interactions for TOR1A

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait APOD Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ATP2B2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C13orf16 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLU Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TOR1A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TOR1A

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Torsin IPR010448 0
Category members Torsin_subgr IPR017378 0


Protein complexes (CORUM database) featuring TOR1A

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1000 TorsinA-TorsinB complex Database 0.04


Categories featuring TOR1A

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005635 nuclear envelope Database 7.22
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0006457 protein folding Database 4.93
Category members GO Category GO:0051082 unfolded protein binding Database 3.74
Category members GO Category GO:0031965 nuclear membrane Database 2.59
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0006986 response to unfolded protein Database 0.62
Category members GO Category GO:0030659 cytoplasmic vesicle membrane Database 0.62
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0006998 nuclear envelope organization Database 0.4
Category members GO Category GO:0043005 neuron projection Database 0.08
Category members Pathway Pathway_405 PID_ALPHA_SYNUCLEIN_PATHWAY 0 0.08
Category members GO Category GO:0004252 serine-type endopeptidase activity Database 0.05
Category members GO Category GO:0019894 kinesin binding Database 0.02
Category members Disease phenotype MYOCLONUS-DYSTONIA_SYNDROME MYOCLONUS-DYSTONIA SYNDROME Database 0
Category members GO Category GO:0005788 endoplasmic reticulum lumen Database 0
Category members GO Category GO:0006979 response to oxidative stress Database 0
Category members GO Category GO:0051085 chaperone mediated protein folding requiring cofactor Database 0
Category members GO Category GO:0051260 protein homooligomerization Database 0


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