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Query: TOMM40

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TOMM40 0 0.566 -0.040 -0.490

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TOMM40 Ubiquitylation K175 0.584 -0.018 _SK(gl)MAIQTQQSK_

Background Information for TOMM40:


Pubmed-TOMM40 »
Uniprot-TOMM40 »
Biogrid-TOMM40 »
ProteomicsDB-TOMM40 »

Tumorportal-TOMM40 »
COSMIC-TOMM40 »
GenomeRNAi-TOMM40 »
Genecards-TOMM40


Protein-protein Interactions for TOMM40
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait TOMM40 Cat. description Hein, Mann, Cell 2015
Category members IP bait CYP2C9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DKFZp686O24166 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FOXRED2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLRF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KRBA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TOMM22 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WNT4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TOMM40
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Porin_Euk/Tom40 IPR027246 0.34


Protein complexes (CORUM database) featuring TOMM40
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TOMM40
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:TBD2_UV_increased Elia et al, 2015 UV increased acetylation events Elia et al. INF
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0046930 pore complex Database 1.57
Category members GO Category GO:0005741 mitochondrial outer membrane Database 0.46
Category members Pathway Pathway_420 KEGG_AMYOTROPHIC_LATERAL_SCLEROSIS_ALS 0 0.39
Category members Pathway Pathway_9 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT 0 0.33
Category members GO Category GO:0031307 integral to mitochondrial outer membrane Database 0.24
Category members GO Category GO:0006811 ion transport Database 0.18
Category members GO Category GO:0055085 transmembrane transport Database 0.12
Category members GO Category GO:0006626 protein targeting to mitochondrion Database 0.11
Category members GO Category GO:0015288 porin activity Database 0.09
Category members GO Category GO:0008320 protein transmembrane transporter activity Database 0.06
Category members GO Category GO:0005742 mitochondrial outer membrane translocase complex Database 0
Category members GO Category GO:0032592 integral to mitochondrial membrane Database 0


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