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Query: TNKS2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TNKS2 0 -0.327 0.000 -0.260

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TNKS2 Ubiquitylation K1081 -0.151 _LIK(gl)GVER_
TNKS2 Ubiquitylation K996 -0.529 _YNILK(gl)IQK_
TNKS2 Ubiquitylation K762 -1.426 _GK(gl)YEICK_
TNKS2 Ubiquitylation K509 -1.494 _AGDVETVK(gl)K_
TNKS2 Ubiquitylation K812 -0.176 -1.693 _GDAALLDAAK(gl)K_
TNKS2 Ubiquitylation K813 -0.176 -1.693 _GDAALLDAAK(gl)K_

Background Information for TNKS2:


Pubmed-TNKS2 »
Uniprot-TNKS2 »
Biogrid-TNKS2 »
ProteomicsDB-TNKS2 »

Tumorportal-TNKS2 »
COSMIC-TNKS2 »
GenomeRNAi-TNKS2 »
Genecards-TNKS2


Protein-protein Interactions for TNKS2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait TNKS Cat. description Hein, Mann, Cell 2015
Category members IP bait TNKS2 Cat. description Hein, Mann, Cell 2015
Category members IP bait AP2M1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BABAM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CELF5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CHD1L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EPN3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM117B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GMDS Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIF1AN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LRP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAPK8IP3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NANOS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RNF166 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SH3BP5L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC35A5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SSSCA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TERF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TNKS2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members SAM IPR001660 0
Category members Ankyrin_rpt IPR002110 0
Category members SAM_2 IPR011510 0
Category members Poly(ADP-ribose)pol_cat_dom IPR012317 0
Category members SAM/pointed IPR013761 0
Category members Ankyrin_rpt-contain_dom IPR020683 0
Category members SAM_type1 IPR021129 0


Protein complexes (CORUM database) featuring TNKS2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1219 Tankyrin 1-tankyrin 2-TRF1 complex Database 0


Categories featuring TNKS2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005635 nuclear envelope Database 7.22
Category members GO Category GO:0000209 protein polyubiquitination Database 2.46
Category members GO Category GO:0019899 enzyme binding Database 1.57
Category members GO Category GO:0000784 nuclear chromosome, telomeric region Database 0.61
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0040014 regulation of multicellular organism growth Database 0.35
Category members GO Category GO:0016055 Wnt signaling pathway Database 0.11
Category members GO Category GO:0035264 multicellular organism growth Database 0.04
Category members GO Category GO:0032212 positive regulation of telomere maintenance via telomerase Database 0.02
Category members GO Category GO:0000139 Golgi membrane Database 0
Category members GO Category GO:0000242 pericentriolar material Database 0
Category members GO Category GO:0003950 NAD+ ADP-ribosyltransferase activity Database 0
Category members GO Category GO:0006471 protein ADP-ribosylation Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0070198 protein localization to chromosome, telomeric region Database 0
Category members GO Category GO:0070213 protein auto-ADP-ribosylation Database 0


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