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Query: TM7SF2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TM7SF2 0 1.708 0.370 0.040 1.044

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TM7SF2 Ubiquitylation K397 0.664 _QCLQK(gl)YGLAWQEYCR_

Background Information for TM7SF2:


Pubmed-TM7SF2 »
Uniprot-TM7SF2 »
Biogrid-TM7SF2 »
ProteomicsDB-TM7SF2 »

Tumorportal-TM7SF2 »
COSMIC-TM7SF2 »
GenomeRNAi-TM7SF2 »
Genecards-TM7SF2


Protein-protein Interactions for TM7SF2
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in TM7SF2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ergosterol_biosynth_ERG4_ERG24 IPR001171 0.46
Category members DUF1295 IPR010721 0.04


Protein complexes (CORUM database) featuring TM7SF2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TM7SF2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor Database 0.03
Category members Pathway Pathway_162 KEGG_STEROID_BIOSYNTHESIS 0 0
Category members Pathway Pathway_164 REACTOME_CHOLESTEROL_BIOSYNTHESIS 0 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members GO Category GO:0006695 cholesterol biosynthetic process Database 0


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