bioLOGIC-db

bioLOGIC Data

Query: THOC5

[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:
Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen

Gene name	Point score	Z-score sums	RNAi high	RNAi low	RNAPII-IP (PI)	CSB-IP	CSB-IP (PI)	Chrom.	Chrom. (PI)
THOC5	0	2.499	-0.860	0.700	0.098	0.341		0.166	0.197

PTM Sites:
Back to Protein Results | Red/green: hit at lower/upper end of the respective screen

Gene name	PTM type	PTM site	UV	UV (PI)	Sequence
THOC5	Ubiquitylation	K222	0.387		_ILKEIEVK(gl)K_
THOC5	Ubiquitylation	K223	0.997		_ILKEIEVKK(gl)_

ProteomicsDB-THOC5 »

Protein-protein Interactions for THOC5

Show screen data for	Category Name and Description	Link to cat description	Data Source
Category members	IP bait BCLAF1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait C17orf85	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait CCDC9	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait HSF2	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait SRSF1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait THOC1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait THOC2	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait THOC5	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait THOC7	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait MRPL12	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait SARNP	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait THOC1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait THOC3	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015

Protein Domains in THOC5

	Domain name	Domain Description	TC-NER relevance -log10(p-value)

Protein complexes (CORUM database) featuring THOC5

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	Corum	351	Spliceosome	Database	9.3
Category members	Corum	770	TREX complex	Database	1.46
Category members	Corum	774	THO complex	Database	0.35

Categories featuring THOC5

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	GO Category	GO:0003723	RNA binding	Database	INF
Category members	GO Category	GO:0005515	protein binding	Database	INF
Category members	GO Category	GO:0005634	nucleus	Database	INF
Category members	GO Category	GO:0005737	cytoplasm	Database	12.81
Category members	GO Category	GO:0008380	RNA splicing	Database	10.77
Category members	GO Category	GO:0016607	nuclear speck	Database	4.84
Category members	GO Category	GO:0006406	mRNA export from nucleus	Database	4.09
Category members	GO Category	GO:0006397	mRNA processing	Database	3.76
Category members	GO Category	GO:0046784	viral mRNA export from host cell nucleus	Database	1.46
Category members	GO Category	GO:0032786	positive regulation of DNA-dependent transcription, elongation	Database	1.27
Category members	GO Category	GO:0000346	transcription export complex	Database	1.18
Category members	GO Category	GO:0000445	THO complex part of transcription export complex	Database	0.67
Category members	GO Category	GO:0030224	monocyte differentiation	Database	0.45
Category members	GO Category	GO:0043231	intracellular membrane-bounded organelle	Database	0.43
Category members	GO Category	GO:0000347	THO complex	Database	0.35
Category members	GO Category	GO:0045111	intermediate filament cytoskeleton	Database	0.26
Category members	GO Category	GO:0060215	primitive hemopoiesis	Database	0.25
Category members	GO Category	GO:0045650	negative regulation of macrophage differentiation	Database	0