bioLOGIC-db

bioLOGIC Data

Query: THOC2

[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:
Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen

Gene name	Point score	Z-score sums	RNAi high	RNAi low	RNAPII-IP (PI)	CSB-IP	CSB-IP (PI)	Chrom.	Chrom. (PI)
THOC2	1	5.488	1.160	-0.300	0.704	0.621	0.548	0.422	0.374

PTM Sites:
Back to Protein Results | Red/green: hit at lower/upper end of the respective screen

Gene name	PTM type	PTM site	UV	UV (PI)	Sequence
THOC2	Phosphorylation	S1417	0.121	0.330	_IDTHPS(ph)PSHSSTVK_
THOC2	Ubiquitylation	K307	-1.093	0.032	_EIAEAK(gl)QIVR_
THOC2	Ubiquitylation	K1084	2.196	0.002	_ATGFDGGNK(gl)ADQLDYENFR_
THOC2	Phosphorylation	S1516		-0.075	_HKSES(ph)PCESPYPNEK_
THOC2	Phosphorylation	S1364		-0.355	_EKEPS(ph)RER_
THOC2	Ubiquitylation	K35		-0.485	_ILSENK(gl)SHDSSTYR_
THOC2	Phosphorylation	S1393	0.261	-0.721	_TPVSGSLKS(ph)PVPR_
THOC2	Ubiquitylation	K415		-1.122	_GSPVNALQNK(gl)R_

ProteomicsDB-THOC2 »

Protein-protein Interactions for THOC2

Show screen data for	Category Name and Description	Link to cat description	Data Source
Category members	IP bait BCLAF1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait C17orf85	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait CCDC9	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait CHMP4B	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait ID2	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait KBTBD7	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait KPNB1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait RNASEH2B	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait SRSF1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait THOC1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait THOC2	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait THOC5	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait THOC7	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait MRPL12	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait THOC1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait THOC3	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015

Protein Domains in THOC2

	Domain name	Domain Description	TC-NER relevance -log10(p-value)

Protein complexes (CORUM database) featuring THOC2

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	Corum	351	Spliceosome	Database	9.3
Category members	Corum	770	TREX complex	Database	1.46
Category members	Corum	774	THO complex	Database	0.35

Categories featuring THOC2

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	DDR Literature	pubmedid:24332808	Marechal et al., 2014 RPA-mediated recruitment		INF
Category members	GO Category	GO:0003723	RNA binding	Database	INF
Category members	GO Category	GO:0005515	protein binding	Database	INF
Category members	GO Category	GO:0008380	RNA splicing	Database	10.77
Category members	Pathway	Pathway_851	KEGG_SPLICEOSOME	0	7.94
Category members	GO Category	GO:0016607	nuclear speck	Database	4.84
Category members	GO Category	GO:0006406	mRNA export from nucleus	Database	4.09
Category members	GO Category	GO:0006397	mRNA processing	Database	3.76
Category members	DDR Literature	pubmedid:19647519	Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation		3.6
Category members	GO Category	GO:0046784	viral mRNA export from host cell nucleus	Database	1.46
Category members	GO Category	GO:0000346	transcription export complex	Database	1.18
Category members	GO Category	GO:0000445	THO complex part of transcription export complex	Database	0.67
Category members	GO Category	GO:0000347	THO complex	Database	0.35
Category members	GO Category	GO:0016973	poly(A)+ mRNA export from nucleus	Database	0