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Query: TFG

This is a cancer-associated gene according to the Sanger cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TFG 0 -1.338 0.490 -0.380
TFG 0 -1.338 0.490 -0.380 2.238

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TFG Ubiquitylation K103 -0.145 -0.235 _PLESSQVK(gl)YLR_
TFG Phosphorylation S197 -0.758 -0.397 _NVM(ox)SAFGLTDDQVSGPPS(ph)APAEDR_
TFG Ubiquitylation K47 0.052 _GK(gl)LLSNDEVTIK_

Background Information for TFG:


Pubmed-TFG »
Uniprot-TFG »
Biogrid-TFG »
ProteomicsDB-TFG »

Tumorportal-TFG »
COSMIC-TFG »
GenomeRNAi-TFG »
Genecards-TFG


Protein-protein Interactions for TFG
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait TFG Cat. description Hein, Mann, Cell 2015
Category members IP bait DUSP14 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RCAN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SEC31A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TFG
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members OPR_PB1 IPR000270 0


Protein complexes (CORUM database) featuring TFG
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TFG
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Human mutations Sanger_cancer_genes Sanger cancer genes Database 4.88
Category members Disease phenotype THYROID_CARCINOMA_PAPILLARY THYROID CARCINOMA PAPILLARY Database 0.72
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members Disease phenotype Papillary_or_follicular_thyroid_carcinoma Papillary or follicular thyroid carcinoma Database 0.09
Category members GO Category GO:0008219 cell death Database 0.08
Category members Pathway Pathway_24 KEGG_PATHWAYS_IN_CANCER 0 0
Category members Pathway Pathway_944 KEGG_THYROID_CANCER 0 0
Category members Disease phenotype Extraskeletal_myxoid_chondrosarcoma Extraskeletal myxoid chondrosarcoma Database 0
Category members GO Category GO:0004871 signal transducer activity Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling Database 0


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