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Query: TFB1M

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TFB1M 0 -2.985 -0.660 0.560 -1.153 -0.409
TFB1M 0 -2.985 -0.660 0.560 -1.397 -0.586

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for TFB1M:





Protein-protein Interactions for TFB1M

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AP4M1 Cat. description Hein, Mann, Cell 2015
Category members IP bait BAIAP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL35 Cat. description Hein, Mann, Cell 2015
Category members IP bait SRP72 Cat. description Hein, Mann, Cell 2015
Category members IP bait YWHAH Cat. description Hein, Mann, Cell 2015
Category members IP bait MECP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPL12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TFB1M Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait YBEY Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TFB1M

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members rRNA_Ade_methylase_transferase IPR001737 0.44
Category members rRNA_Ade_methylase_Trfase_N IPR020598 0.44
Category members SAM-dependent_MTases-like IPR029063 0.04


Protein complexes (CORUM database) featuring TFB1M

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TFB1M

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity Database 0.82
Category members GO Category GO:0042645 mitochondrial nucleoid Database 0.61
Category members GO Category GO:0000154 rRNA modification Database 0.44
Category members Disease phenotype Mitochondrial_non-syndromic_sensorineural_deafness Mitochondrial non-syndromic sensorineural deafness Database 0.33
Category members GO Category GO:0008649 rRNA methyltransferase activity Database 0.04
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0


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