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Query: TEAD1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TEAD1 0 2.863 -0.020 0.420

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TEAD1 Ubiquitylation K50 1.259 0.615 _IILSDEGK(gl)MYGR_
TEAD1 Phosphorylation S11 0.569 _(ac)MEPSSWSGSES(ph)PAENMER_
TEAD1 Ubiquitylation K262 -0.150 _VCSFGK(gl)QVVEK_

Background Information for TEAD1:





Protein-protein Interactions for TEAD1

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait YAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TEAD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TEAD2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TEAD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VGLL4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WWTR1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TEAD1

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members TEA/ATTS IPR000818 0
Category members TEF IPR016361 0


Protein complexes (CORUM database) featuring TEAD1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TEAD1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members Pathway Pathway_90 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION 0 0.88
Category members GO Category GO:0035329 hippo signaling Database 0.68
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0006367 transcription initiation from RNA polymerase II promoter Database 0.25
Category members Pathway Pathway_1 REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM 0 0.23
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0048339 paraxial mesoderm development Database 0.09
Category members Pathway Pathway_822 REACTOME_GENERIC_TRANSCRIPTION_PATHWAY 0 0.09
Category members GO Category GO:0042127 regulation of cell proliferation Database 0.06
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members Pathway Pathway_939 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION 0 0
Category members GO Category GO:0003143 embryonic heart tube morphogenesis Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0007507 heart development Database 0
Category members GO Category GO:0030903 notochord development Database 0
Category members GO Category GO:0048368 lateral mesoderm development Database 0


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