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Query: TBL3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TBL3 0 4.120 -1.370 2.030 0.216 0.205 0.850 0.207 0.445

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TBL3 Ubiquitylation K458 -0.509 0.676 _ALLSK(gl)NTAPDNGPILLQAQTTQR_
TBL3 Ubiquitylation K664 -0.410 _QQELDNLLHEK(gl)R_
TBL3 Ubiquitylation K593 -0.545 _LWTIK(gl)NNECVR_

Background Information for TBL3:


Pubmed-TBL3 »
Uniprot-TBL3 »
Biogrid-TBL3 »
ProteomicsDB-TBL3 »

Tumorportal-TBL3 »
COSMIC-TBL3 »
GenomeRNAi-TBL3 »
Genecards-TBL3


Protein-protein Interactions for TBL3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait EXOSC1;RP11 Cat. description Hein, Mann, Cell 2015
Category members IP bait EXOSC5 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPU Cat. description Hein, Mann, Cell 2015
Category members IP bait KTN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NOP56 Cat. description Hein, Mann, Cell 2015
Category members IP bait RRBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RUVBL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SRP72 Cat. description Hein, Mann, Cell 2015
Category members IP bait ARHGAP25 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DKKL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HSD3B2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBM4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TBL3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WD40_repeat_dom IPR017986 1.39
Category members Quinonprotein_ADH-like_supfam IPR011047 0.56
Category members WD40_repeat IPR001680 0.52
Category members G-protein_beta_WD-40_rep IPR020472 0.12


Protein complexes (CORUM database) featuring TBL3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1211 Ubiquitin E3 ligase (AHR, ARNT, DDB1, TBL3, CUL4B, RBX1) Database 0.05


Categories featuring TBL3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members DDR Literature pubmedid:TBD1_UV_decreased Elia et al, 2015 UV decreased acetylation events Elia et al. 10.54
Category members GO Category GO:0006364 rRNA processing Database 2.47
Category members GO Category GO:0032040 small-subunit processome Database 0.17
Category members GO Category GO:0005057 receptor signaling protein activity Database 0
Category members GO Category GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger Database 0


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