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Query: TBCA

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TBCA 1 4.392 -0.930 1.040

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TBCA Ubiquitylation K31 0.513 0.494 _VMYEKEAK(gl)_
TBCA Ubiquitylation K52 -0.192 0.447 _K(gl)QAEILQESR_
TBCA Ubiquitylation K51 0.087 0.331 _AEDGENYDIK(gl)K_
TBCA Ubiquitylation K12 2.858 _IK(gl)TGVVKR_
TBCA Ubiquitylation K17 1.648 _IKTGVVK(gl)R_
TBCA Ubiquitylation K28 0.435 _VM(ox)YEK(gl)EAK_
TBCA Ubiquitylation K39 0.266 _QQEEKIEK(gl)MR_

Background Information for TBCA:


Pubmed-TBCA »
Uniprot-TBCA »
Biogrid-TBCA »
ProteomicsDB-TBCA »

Tumorportal-TBCA »
COSMIC-TBCA »
GenomeRNAi-TBCA »
Genecards-TBCA


Protein-protein Interactions for TBCA
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait HMG2L1;HMGXB4 Cat. description Hein, Mann, Cell 2015


Protein Domains in TBCA
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members CofA_tubulin-bd IPR004226 0.2


Protein complexes (CORUM database) featuring TBCA
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TBCA
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0006457 protein folding Database 4.93
Category members GO Category GO:0051082 unfolded protein binding Database 3.74
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0051087 chaperone binding Database 1.69
Category members GO Category GO:0015630 microtubule cytoskeleton Database 1.34
Category members GO Category GO:0005874 microtubule Database 1.21
Category members Pathway Pathway_742 REACTOME_PROTEIN_FOLDING 0 0.9
Category members GO Category GO:0051084 'de novo' posttranslational protein folding Database 0.63
Category members Pathway Pathway_1295 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY 0 0.07
Category members GO Category GO:0007021 tubulin complex assembly Database 0.01
Category members GO Category GO:0007023 post-chaperonin tubulin folding pathway Database 0


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