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Query: SVIL

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SVIL 1 4.466 -1.650 2.870 -1.295 -0.292 0.646 0.534

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SVIL Ubiquitylation K697 0.800 _LSVAAK(gl)R_
SVIL Phosphorylation S707 0.430 0.681 _EM(ox)EKS(ph)FDEQNVPK_
SVIL Phosphorylation S769 0.192 0.347 _LPS(ph)PTVAR_
SVIL Phosphorylation S968 0.381 0.329 _YGS(ph)FEEAEASYPILNR_
SVIL Phosphorylation S914 0.522 0.237 _FSSS(ph)IENSDSPVR_
SVIL Phosphorylation S913 0.231 0.034 _FSS(ph)SIENSDSPVR_
SVIL Phosphorylation S245 0.066 0.019 _DSSFTEVPRS(ph)PK_
SVIL Phosphorylation S263 -0.874 _SPS(ph)FGDPQLS(ph)PEAR_
SVIL Phosphorylation S270 -0.874 _SPS(ph)FGDPQLS(ph)PEAR_
SVIL Phosphorylation S1120 -1.875 _TPTGEGLLDS(ph)PSK_
SVIL Phosphorylation S1122 -0.368 _TPTGEGLLDSPS(ph)K_

Background Information for SVIL:


Pubmed-SVIL »
Uniprot-SVIL »
Biogrid-SVIL »
ProteomicsDB-SVIL »

Tumorportal-SVIL »
COSMIC-SVIL »
GenomeRNAi-SVIL »
Genecards-SVIL


Protein-protein Interactions for SVIL
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTB Cat. description Hein, Mann, Cell 2015
Category members IP bait ACTR1B Cat. description Hein, Mann, Cell 2015
Category members IP bait ACTR2 Cat. description Hein, Mann, Cell 2015
Category members IP bait ADD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ANLN Cat. description Hein, Mann, Cell 2015
Category members IP bait CALML3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CAPZA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CD14 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDK2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CENPE Cat. description Hein, Mann, Cell 2015
Category members IP bait CORO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait DBN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait DNAJC7 Cat. description Hein, Mann, Cell 2015
Category members IP bait EEF1A1;EEF1A1P5 Cat. description Hein, Mann, Cell 2015
Category members IP bait FLNA Cat. description Hein, Mann, Cell 2015
Category members IP bait FLNB Cat. description Hein, Mann, Cell 2015
Category members IP bait FLOT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait FLOT2 Cat. description Hein, Mann, Cell 2015
Category members IP bait IQGAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIAA1430 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF3C Cat. description Hein, Mann, Cell 2015
Category members IP bait KLC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait LIMA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait LLGL2 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAPRE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH10 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH11 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH13 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYL12A;MYL12B Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO18A Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO19 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO5C Cat. description Hein, Mann, Cell 2015
Category members IP bait NES Cat. description Hein, Mann, Cell 2015
Category members IP bait PDLIM7 Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP1CB Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP1CC Cat. description Hein, Mann, Cell 2015
Category members IP bait SEPT9 Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNPO Cat. description Hein, Mann, Cell 2015
Category members IP bait TMOD3 Cat. description Hein, Mann, Cell 2015
Category members IP bait TPM1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TPM4 Cat. description Hein, Mann, Cell 2015
Category members IP bait CAPZA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMOD3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SVIL
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Gelsolin-like_dom IPR007123 0.09
Category members Villin_headpiece IPR003128 0.03
Category members Villin/Gelsolin IPR007122 0


Protein complexes (CORUM database) featuring SVIL
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 725 P2X7 receptor signalling complex Database 0.53


Categories featuring SVIL
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003779 actin binding Database 5.41
Category members GO Category GO:0015629 actin cytoskeleton Database 2.22
Category members GO Category GO:0043034 costamere Database 1.42
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0051015 actin filament binding Database 0.99
Category members Pathway Pathway_880 PID_AR_PATHWAY 0 0.58
Category members GO Category GO:0002102 podosome Database 0.3
Category members GO Category GO:0071437 invadopodium Database 0.25
Category members GO Category GO:0007010 cytoskeleton organization Database 0
Category members GO Category GO:0007519 skeletal muscle tissue development Database 0
Category members GO Category GO:0030054 cell junction Database 0


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