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Query: SUPT4H1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SUPT4H1 1 -0.184 2.420 -1.150 0.026 -0.438 1.185 0.435

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SUPT4H1 Ubiquitylation K8 -1.392 _(ac)ALETVPK(gl)DLR_

Background Information for SUPT4H1:


Pubmed-SUPT4H1 »
Uniprot-SUPT4H1 »
Biogrid-SUPT4H1 »
ProteomicsDB-SUPT4H1 »

Tumorportal-SUPT4H1 »
COSMIC-SUPT4H1 »
GenomeRNAi-SUPT4H1 »
Genecards-SUPT4H1


Protein-protein Interactions for SUPT4H1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait RPRD1B Cat. description Hein, Mann, Cell 2015
Category members IP bait SUPT5H Cat. description Hein, Mann, Cell 2015
Category members IP bait C4orf43 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DOK4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGF9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PAK7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SUPT4H1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RPABC4/Spt4 IPR029040 0


Protein complexes (CORUM database) featuring SUPT4H1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2860 DSIF complex (DRB sensitivity-inducing factor complex) Database 0.05
Category members Corum 2861 DSIF complex (DRB sensitivity-inducing factor complex) Database 0.05


Categories featuring SUPT4H1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0016032 viral process Database INF
Category members Pathway Pathway_197 REACTOME_HIV_INFECTION 0 12.07
Category members Pathway Pathway_376 REACTOME_HIV_LIFE_CYCLE 0 9.45
Category members Pathway Pathway_348 REACTOME_TRANSCRIPTION 0 9
Category members Pathway Pathway_374 REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE 0 7.57
Category members GO Category GO:0006338 chromatin remodeling Database 4.95
Category members GO Category GO:0050434 positive regulation of viral transcription Database 4.8
Category members Pathway Pathway_360 REACTOME_FORMATION_OF_RNA_POL_II_ELONGATION_COMPLEX_ 0 3.35
Category members Pathway Pathway_375 REACTOME_RNA_POL_II_TRANSCRIPTION 0 2.46
Category members GO Category GO:0006368 transcription elongation from RNA polymerase II promoter Database 2.03
Category members Pathway Pathway_363 REACTOME_RNA_POL_II_PRE_TRANSCRIPTION_EVENTS 0 1.84
Category members Pathway Pathway_367 REACTOME_ELONGATION_ARREST_AND_RECOVERY 0 1.67
Category members Pathway Pathway_361 REACTOME_FORMATION_OF_THE_HIV1_EARLY_ELONGATION_COMPLEX 0 1.57
Category members GO Category GO:0032786 positive regulation of DNA-dependent transcription, elongation Database 1.27
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members Pathway Pathway_364 REACTOME_ABORTIVE_ELONGATION_OF_HIV1_TRANSCRIPT_IN_THE_ABSENCE_OF_TAT 0 0.35
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0046982 protein heterodimerization activity Database 0.28
Category members GO Category GO:0006357 regulation of transcription from RNA polymerase II promoter Database 0.19
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0032044 DSIF complex Database 0.05
Category members GO Category GO:0032785 negative regulation of DNA-dependent transcription, elongation Database 0.05
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter Database 0


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