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Query: SUPT16H

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SUPT16H 0 5.738 0.440 -0.660 1.250 0.965 1.480 0.663 0.440

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SUPT16H Ubiquitylation K366 0.618 0.185 _EGSLVINSK(gl)NQYK_
SUPT16H Ubiquitylation K370 0.755 0.185 _EGSLVINSK(gl)NQYK_
SUPT16H Ubiquitylation K504 -0.091 0.104 _LTEQKGEQQIQK(gl)AR_
SUPT16H Ubiquitylation K497 -0.023 0.099 _RLTEQK(gl)GEQQIQK_
SUPT16H Ubiquitylation K490 -0.413 -0.183 _ELAAQLNEEAK(gl)R_
SUPT16H Ubiquitylation K674 -0.935 -1.355 _DLYIRPNIAQK(gl)R_
SUPT16H Ubiquitylation K335 0.728 _ICDVYNAVMDVVKK(gl)_
SUPT16H Ubiquitylation K513 -1.189 _KSNVSYK(gl)NPSLMPK_
SUPT16H Ubiquitylation K606 -1.524 _ASNIK(gl)APGEQTVPALNLQNAFR_
SUPT16H Ubiquitylation K781 -0.148 _TAFK(gl)NFIEK_

Background Information for SUPT16H:


Pubmed-SUPT16H »
Uniprot-SUPT16H »
Biogrid-SUPT16H »
ProteomicsDB-SUPT16H »

Tumorportal-SUPT16H »
COSMIC-SUPT16H »
GenomeRNAi-SUPT16H »
Genecards-SUPT16H


Protein-protein Interactions for SUPT16H
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATRX Cat. description Hein, Mann, Cell 2015
Category members IP bait CBX1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CENPQ Cat. description Hein, Mann, Cell 2015
Category members IP bait DAXX Cat. description Hein, Mann, Cell 2015
Category members IP bait EIF3A Cat. description Hein, Mann, Cell 2015
Category members IP bait EIF3E Cat. description Hein, Mann, Cell 2015
Category members IP bait EIF3I Cat. description Hein, Mann, Cell 2015
Category members IP bait ETAA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPU Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait NPM1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL35 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPRD1B Cat. description Hein, Mann, Cell 2015
Category members IP bait SRP72 Cat. description Hein, Mann, Cell 2015
Category members IP bait ALX3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait APLF Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CENPA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CETN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CHD1L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait H2AFX Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait H2AFY2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H2BA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H3A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H4A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait L3MBTL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MACROD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NAA40 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait POLB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RNF146 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPA4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SIX2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPIN2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SSRP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TEAD2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TIPIN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR76 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait XPC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait XRCC6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SUPT16H
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members DUF1747 IPR013719 0.35
Category members Pept_M24_structural-domain IPR000994 0


Protein complexes (CORUM database) featuring SUPT16H
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1223 H2AX complex, isolated from cells without IR exposure Database 8.51
Category members Corum 1230 WINAC complex Database 3.79
Category members Corum 929 CEN complex Database 3.25
Category members Corum 934 FACT-NEK9 complex Database 0.79
Category members Corum 2639 HES1 promoter-Notch enhancer complex Database 0.45
Category members Corum 936 FACT complex Database 0.35
Category members Corum 938 FACT complex, UV-activated Database 0.35


Categories featuring SUPT16H
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0016032 viral process Database INF
Category members Pathway Pathway_197 REACTOME_HIV_INFECTION 0 12.07
Category members Pathway Pathway_376 REACTOME_HIV_LIFE_CYCLE 0 9.45
Category members Pathway Pathway_348 REACTOME_TRANSCRIPTION 0 9
Category members Pathway Pathway_374 REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE 0 7.57
Category members GO Category GO:0050434 positive regulation of viral transcription Database 4.8
Category members GO Category GO:0005694 chromosome Database 3.87
Category members Pathway Pathway_360 REACTOME_FORMATION_OF_RNA_POL_II_ELONGATION_COMPLEX_ 0 3.35
Category members GO Category GO:0006260 DNA replication Database 3.34
Category members GO Category GO:0006337 nucleosome disassembly Database 3
Category members Pathway Pathway_375 REACTOME_RNA_POL_II_TRANSCRIPTION 0 2.46
Category members GO Category GO:0006368 transcription elongation from RNA polymerase II promoter Database 2.03
Category members Pathway Pathway_363 REACTOME_RNA_POL_II_PRE_TRANSCRIPTION_EVENTS 0 1.84
Category members Pathway Pathway_367 REACTOME_ELONGATION_ARREST_AND_RECOVERY 0 1.67
Category members GO Category GO:0032786 positive regulation of DNA-dependent transcription, elongation Database 1.27
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96


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