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Query: STX8

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
STX8 0 2.214 0.283 0.633

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
STX8 Ubiquitylation K117 0.144 1.154 _SSLMSEEAK(gl)R_
STX8 Ubiquitylation K98 -0.839 -0.064 _LLLASFK(gl)NEGAEPDLIR_

Background Information for STX8:


Pubmed-STX8 »
Uniprot-STX8 »
Biogrid-STX8 »
ProteomicsDB-STX8 »

Tumorportal-STX8 »
COSMIC-STX8 »
GenomeRNAi-STX8 »
Genecards-STX8


Protein-protein Interactions for STX8
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait SEC24C Cat. description Hein, Mann, Cell 2015
Category members IP bait SNAP29 Cat. description Hein, Mann, Cell 2015
Category members IP bait AP1S2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait AP2M1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ASPH Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CEP170 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLEC12A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLINT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DTNBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GDPD5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPR156 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IPPK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LPAR1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAP7D2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MED21 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NAPG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SEC22B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SRPRB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STAMBPL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STX11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STX12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STX18 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STX3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STX6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STX7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STXBP6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM171 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRDN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VAMP4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VTI1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in STX8
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members T_SNARE_dom IPR000727 0.54


Protein complexes (CORUM database) featuring STX8
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring STX8
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0031625 ubiquitin protein ligase binding Database 2.54
Category members GO Category GO:0006886 intracellular protein transport Database 2.48
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members Pathway Pathway_1261 KEGG_SNARE_INTERACTIONS_IN_VESICULAR_TRANSPORT 0 1.52
Category members GO Category GO:0006906 vesicle fusion Database 1.28
Category members GO Category GO:0016192 vesicle-mediated transport Database 1.1
Category members GO Category GO:0005765 lysosomal membrane Database 0.82
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0031201 SNARE complex Database 0.49
Category members GO Category GO:0008333 endosome to lysosome transport Database 0.49
Category members Pathway Pathway_1262 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS 0 0.2
Category members GO Category GO:0005484 SNAP receptor activity Database 0.2
Category members Pathway Pathway_1263 REACTOME_BOTULINUM_NEUROTOXICITY 0 0.07
Category members Pathway Pathway_139 REACTOME_NEURONAL_SYSTEM 0 0
Category members GO Category GO:0006810 transport Database 0
Category members GO Category GO:0031902 late endosome membrane Database 0


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