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Query: SSR1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SSR1 0 -0.535 -0.220 -0.180
SSR1 0 -0.535 -0.220 -0.180 0.456 0.400

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SSR1 Phosphorylation S268 -0.607 -0.604 _VEM(ox)GTSSQNDVDMSWIPQETLNQINKAS(ph)PR_

Background Information for SSR1:


Pubmed-SSR1 »
Uniprot-SSR1 »
Biogrid-SSR1 »
ProteomicsDB-SSR1 »

Tumorportal-SSR1 »
COSMIC-SSR1 »
GenomeRNAi-SSR1 »
Genecards-SSR1


Protein-protein Interactions for SSR1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait EZH2 Cat. description Hein, Mann, Cell 2015
Category members IP bait HUWE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SORT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBGCP5 Cat. description Hein, Mann, Cell 2015
Category members IP bait ERGIC3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SSR1
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring SSR1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SSR1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_456 REACTOME_TRANSLATION 0 INF
Category members Pathway Pathway_459 REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE 0 INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0006412 translation Database INF
Category members GO Category GO:0006614 SRP-dependent cotranslational protein targeting to membrane Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0030968 endoplasmic reticulum unfolded protein response Database 1.35
Category members GO Category GO:0006987 activation of signaling protein activity involved in unfolded protein response Database 1.26
Category members Pathway Pathway_147 REACTOME_UNFOLDED_PROTEIN_RESPONSE 0 1.08
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members Pathway Pathway_146 REACTOME_DIABETES_PATHWAYS 0 0.39
Category members GO Category GO:0006613 cotranslational protein targeting to membrane Database 0.31
Category members Pathway Pathway_148 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S 0 0.11
Category members GO Category GO:0008284 positive regulation of cell proliferation Database 0


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